femara and bone loss

I was on Femara and the bone pain was horrible. they wasn't any osteoporous Femara causes swelling and bone pain I switch to Arimidex after being off Femara for 2 weeks and am not having the pain. Please look in to Femara side effects and possible changeing to another drug. I even was in physical therapy for two months because I thought it was me but no it was the drug..

I have had increasing debilitating severe pain in left hip, left foot and both hands. DEXA scan showed increased bone density loss to that of a DEXA scan done before bc (ordered by gastro due to 30+ yrs of steroids). BC surgeon prescribed Fosamax and Calcichew/Vit.D3. A bone scan showed osteo arthritis in both hips, hands and feet. No meds prescribed. I am on weekly injections of 12.5 mg methotrexate for Crohn's.

What Femara does, however, is that it can have a side effect in bone metabolism causing decreased bone mineralization that can cause bone pains and sometimes may lead to increased incidence of fractures. Hope this helps. Regards.

I take calcium supplements and have regular bone scans because estrogen blockers can cause bone loss, which is usually the cause of the bone pain. So far, I am holding my own, though. However, I started out with bone density readings off the chart so it might take me a little more time to show any loss. Other side effects are insomnia (if taken before bed....I take mine in the morning, now), minor hair loss, and hot flashes.

I was on femara and the pain was so bad. I thought my back and knees hurt from exercise the pain was from femara. all my bones hurt. when i went off it within 10 days the pain was gone. I am now on aromatex although not purfect the pain is minimal and if i swim alot it helps with the pain. there are other drugs that do the same.

I was on tamoxifen for 5 years and have been on femara for 3. The back pain and joint pain has gotten horrible. I can no longer stand up straight or walk very far. I am 64 and afraid I will no longer be able to walk soon. I stopped femara 4 days ago. I wonder if any else has had this problem with the very severe joint pain, and if it will go away any time soon. The pain and quality of my life is so bad that I am taking the chance.

Hi - after I finished chemo and starting rads in 2003 I was prescribed tamoxifen, took it for 2 months and my Oncologist changed me to Arimidex (one of the aromatose inhibitors) which I think has a 50% better prognosis for non recurrence than the old "gold standard" tamoxifen. I was thrilled, as it had just come on to the market here in England. However, 4 yrs down the line, I stopped it 4 weeks ago, due to severe bone pain (hips, hands and feet) and the pain has gone!

I have a good diet, take exercise and my bone density is normal. I am 74.

My last session of chemo was in july 2010. Radiation ended in sept 2010. I have been taking Tab Femara plus tab bone one and zomata (inj) from october-2010. Now I started to have in left knee joint pain. I have spoken to my doctor who advises, it could be post chemo/medication caused and may go away with a passage of time. Now i am going to undertake Bone Scan on advise of doctor. This Bone Scan was earlier done which was okeyed by doctor.. What do you suggest I do,. Your advise?

Greetings: I have hepatitis C and am taking 2.5 Femara. My oncologist and my Hep C doc are at odds about the amount i should take. My Hep C doc thinks i should only be taking 1/2 that amount. I'm at a loss as to what to do. I recently had a liver biopsy which showed no scarring and have had Hep C for almost 30 years. I am worried that the Femara may be doing untold damage to my liver. Any help you can provide would be greatly appreciated!

Had a bone marrow test several years ago due to irregularity in white and red blood count. The bone marrow test results were ok but my problem with blood counts were never explained. My question, does the risk of Femara, especially with my history out weigh the small benefits of Femara?

Hi there. Shortness of breath is not a listed common (and even uncommon) side effects of femara and similar drugs. Femara's side effects most commonly involve the bones and the bone mineralization process with more tendency towards osteoporosis and sometimes fractures. I suggest that you inform your doctor about this, as this may be due to anxiety, lung, or heart problem (which can be a side effect of previous treatment like chemotherapy or radiation therapy). Regards and God bless.

D3 twice daily, as the steroids (30+ yrs) and 4 yrs of Arimidex (an aromatose inhibitor, which I am trying to change to Aromasin or Femara) for breast cancer have caused low bone density and ostepeonia. I had two spontaneous fractures in both feet last summer so am concerned about a hip fracture. I saw a Professor of Endocrinology in Feb last who said I was on the optimum treatment for both breast cancer and Crohn's - have to trust the docs sometime I guess.

This drug can cause decrease in bone density and bone mass leading to osteoporosis and sometimes increased tendency to have fractures. If standard pain medications are not helping with these symptoms, I believe that you may discuss with your doctor regarding shifting to a different drug class such as tamoxifen (though tamoxifen has a different side effect profile, mainly from cardiac and vascular side effects).

Im in recurrence of OVCA after 15thms. did chemo and avastin trial. Thank you.

ALP elevations can be related to various conditions such as liver disease, bone disease, hyperparathyroidism, and mono, and also can be associated with numerous medications. They don't tell a lot, unless correlated with other clinical findings. I know that it is difficult not to worry about recurrence anytime something changes, but try not to "totally" freak yet. I think your Dr.

m=2 Additional side effects for both Femara and tamoxifen are heart attack, thromboembolic events, endometrial cancer and second malignancies. bOTH THE DRUGS CAN CAUSE GAIN IN WEIGHT.

I have noticed some visual disturbances including vitreous floaters. I have been to the opthamologist who says there is no correlation between Femara and my eyes. Has anyone heard anything to the contrary.

That sounds like it should be good for you if you are ovulating on your own and aren't having any other problems. I was on femara and avandia (for PCOS), and I had to have a trigger shot (because I don't ovulate on my own). But I got pregnant on my second month of femara (with IUI). And that was after 6 years of trying and being on clomid for a really long time. So I really believe in femara!

Mum was diagnosed March 2005 OVCA stage 3, reoccurance 2007 and 2008, each time treated with carbo and taxol. Currently in remission. Dr put her on femera and tamoxifen but since being on tamoxifen she has had 2 DVTs in her right leg. Dr today stopped them and put her on warfrine (sorry about the spelling). Dr thinks she might have to be on this for the rest of her life. Dr also said she expects mums cancer to come back at some point but her cancer is very slow growing.

December 14, 2009 (San Antonio, Texas) — New results coming from 2 mature trials with exemestane (Aromasin, Pfizer) suggest that this aromatase inhibitor differs slightly from the other 2 available products, letrozole (Femara, Novartis) and anastrozole (Arimidex, AstraZeneca). Although all 3 are aromatase inhibitors, exemestane is a steroidal product that binds irreversibly to the estrogen receptor; the other 2 products are both nonsteroidal and are reversible inhibitors.

I, too, have joint pain and swelling in hands (and sometimes feet) w/femara. I have developed a trigger finger and dequervains tendonitis in bilateral wrist w/thumb pain. Had to go off med for a month and also have sites injected w/cortisone. Never had any of this before. Oncologist said she had seen trigger finger before no dequervains tendonitis? Wondering if anyone out there has had any of these side effects? And what do you think of this? I am miserable w/all this discomfort.

My husband and I ttc in 2005, but with no luck (6 rounds of clomid) I was obese and in 2009, I had gastric bypass and have lost 185+ lbs. I am now close to 4 years out and my husband and I have started TTC again since July of this year. My period started coming on its on about a month and half after taking my last birth control pill. In December, my gyno put me on Metformin 750mg 2 times a day. Then in January added 5mg Femara (days 3-7), also did that in Feb.

Also, I have read that Clomid can lead to endo coming back quicker. Is this true and is it also true of Femara? I am very worried that then endo will come back, and I would really like the Femara to work well!! Thank You!

I used Clomid for one cycle and it worked. Did you ovulate on Femara? Some women with PCOS have better luck with Femara than they had with Clomid.

The surgery worked best on my lower teeth, slowing down the bone loss significantly and rebuilding bone/tooth connection (that's what the gortex is for. That type of surgery is even more advanced now, I think). It didn't have as much success with my more advanced upper teeth. You have to identify all compromised teeth and undergo aggressive treatment (surgery, root planing..), and then take very good care of your teeth and gums for the rest of your life.

dentist said I have 50% bone loss. Is there anything else I can do to prevent further bone loss?

Femara and bone loss

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