Felodipine solubility

Common Questions and Answers about Felodipine solubility

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Avatar n tn However, since the accidental discovery of an interaction between the calcium channel blocker, felodipine, with grapefruit juice,1 it has now become evident that grapefruit juice has the potential to alter the plasma concentrations of many medications when they are taken by mouth. In some cases, this may result in undesirable clinical effects of medications.
Avatar m tn Methadone has a slow metabolism and very high fat solubility, making it longer lasting than morphine-based drugs. Methadone has a typical elimination half-life of 15 to 60 hours with an average of i would say about 22. However, metabolism rates vary greatly between individuals, up to a factor of 100 ranging from as few as 4 hours to as many as 130 hours, or even 190 hours. So it's hard to say.
Avatar m tn The water solubility of bilirubin allows the bilirubin to be excreted into bile. (Bile then is used to digest fats.) Total bilirubin, if I remember correctly, is the conjugated hemoglobin, since there is also another portion that is not conjugated. What the elevated total bilirubin means at this point is 'something' is going on, but you may need more information before your doc can determine the cause.
Avatar f tn Hormones like estrogen (in birth control pills or hormone replacement therapy) and testosterone Blood pressure medicines called calcium channel blockers (such as nifedipine, amlodipine, diltiazem, felodipine, and verapamil) Steroids Antidepressants, including MAO inhibitors (such as phenelzine and tranylcypromine) and tricyclics (such as nortriptyline, desipramine, and amitriptyline) Home Care Elevate your legs above your heart while lying down.
Avatar n tn hello 5 weeks ago i woke up to find my left eye had what i can only describe has a frosty shadow over it i left it for two weeks thinking it was just floaters no change so went to the doctors who gave me a blood pressure test found it was high and put me on felodipine prolonged release tablets 2.
Avatar m tn The main requirements for them are (1) high IFN-inducing activity, (2) absence of side effects, (3) wide spectrum of antimicrobial activity, (4) broad therapeutic security and, (5) good solubility in water and biologic liquids. IFN inducers stimulate IFN production in different cells and organs, and that determines the strategy for their application. Amixin (OOO "Lancepharm," Moscow, Russia) induces IFN-?/? production mostly in T cells. Cycloferon (NTFF "Polysan," St.
Avatar n tn However, factors that can affect absorption include oral pH, salivary enzymes, lipid solubility, and molecular weight (molecules may be too large to pass through the mucous membranes). A sublingual product, specifically created to ensure effective absorption, is recommended.
Avatar n tn In June '08 I was sitting watching TV when my left side from my head down to my leg became stiff and numb. Went to the ER and checked by 5 neuronogists, had scans, MRI & other tests. Their consensus was a brain event in the rt. thalemus. For 2 & 1/2 yrs I was living with a 5 out of 10 sensation but last Dec. '10 as I was having dinner, the sensation became worse like an 8 out of 10 and I'm having increased trouble moving my whole left side.
Avatar m tn Coadministration with the hepatitis C virus (HCV) NS3/4A protease inhibitors, boceprevir and telaprevir, may increase the plasma concentrations and pharmacologic effects of calcium channel blockers, especially the dihydropyridines (e.g., amlodipine, felodipine, nicardipine, nifedipine, nisoldipine). The mechanism involves inhibition of intestinal and hepatic CYP450 3A4, the isoenzyme primarily responsible for the metabolic clearance of most calcium channel blockers.
Avatar f tn I am active, never sick but use eyedrops for Glaucoma, very slightly elevated blood pressure for which I take a mild 5 mg. Felodipine tab and vytorin for slightly elevated cholestrol. My chol. ratio with meds is 2.3. The last week I have had a great slowing of my pulse. For three days it didn't get over 42 and on one day if got down as low as 37 and then 38 and stayed there all day. My blood pressure has been about the same as it always is....
Avatar f tn Hormones like estrogen (in birth control pills or hormone replacement therapy) and testosterone, Blood pressure medicines called calcium channel blockers (such as nifedipine, amlodipine, diltiazem, felodipine, and verapamil), Steroids, Antidepressants, including MAO inhibitors (such as phenelzine and tranylcypromine) and tricyclics (such as nortriptyline, desipramine, and amitriptyline).
Avatar n tn (By the way, although losartan is currently being researched in Johns Hopkins clinical trials, other ARBs such as telmisartan are probably most effective given their increased lipid solubility and thus increased tissue penetration.) I strongly encourage you to visit www.marfanlife.net and find the very lengthy thread titled "Losartan" or something to that effect. Probably some of the most important reading of your life.
Avatar n tn i am 62+ male i have been having hypothyrodism for around 2 decades this was discovered when i had elevated liver enzymes now its normal i am having hypertension right branch bundle block perhaps congenital i took fosamax weekly for osteoporosis for about 5 years i had enlarged prostrate gland recent abdominal echo report say size normal i am on urimax futher for hypertension i am on felodipine 5mg and losartan potasium 25 mg and it is under control I was recently admitted to hospital for a tra
Avatar m tn the brain is affected quickly as alcohol will cross what is called the blood-brain barrier due to its solubility. this can compromise involuntary actions such as heartbeat, breathing and gag reflex. organs such as the liver and pancreas can suffer tissue destruction resulting in everything from lowered function and scarring to complete organ failure. for diagnosing existing damage, your doctor can order bloodwork including a liver panel to check things like enzyme levels.
Avatar n tn Insulin glargine is a human insulin analog that has been designed to have low aqueous solubility at neutral pH. At pH 4, as in the LANTUS injection solution, it is completely soluble. After injection into the subcutaneous tissue, the acidic solution is neutralized, leading to formation of microprecipitates from which small amounts of insulin glargine are slowly released, resulting in a relatively constant concentration/time profile over 24 hours with no pronounced peak.
Avatar n tn I'm a 38 year old male with a 16 or so year history of "noticeable" PVCs. They weren't particuarly frequent (maybe a few per hour) but annoying. My doctor tried beta blockers (Toprol, Atenolol) and a calcium channel blocker (cardizem), none of which had any effect on my PVCs. ECGs and an echocardiogram were all normal. I eventually learned to live with them and for the most part ignore them. About a year ago I was experiencing some chest pain so I had a cardiac workup.
Avatar m tn I have been prescribed 10mg of lisinopril, 5mg of felodipine daily and then a few visits to a very enthusiastic GP he has put me on 2x 95mg metoprolol succinate daily because I had a high heart rate in all my readings. My BP and heart rate now seems to be okay when I get it checked but this seems like a very high dose of metoprolol and I'm getting worried it's going to cause me some damage in the long term.
Avatar m tn ve been on the meds for almost 8 yrs of which 3 yrs of that serving as a Drill Sgt. I can also deploy to Iraq or Afghanistan using Felodipine and was curious as to what harm would 61 days of Ranger School do.
Avatar m tn Hi & Welcome! A BB King fan, eh? Well, Congratulations on your 3 Days off Subs! While the majority of people I've known (including myself) to come off Bupe experience w/d's b/w 24 & 48 hours , some have reported that it 'ramps up'/intensifies between 72 - 96 hrs. Have you had any kind of opiate habit before? If not, it's just possible that you might experience milder w/d's than someone w/ a longer history.
1365078 tn?1284494484 I put on some weight (30 lbs in 6 weeks) when I quit smoking and also was taken off of fluoxitine, felodipine and spriolactane.
Avatar m tn Because of its small size, Ru can be easily conjugated to any protein ligand using standard chemistries without affecting immunoreactivity or solubility of the protein. In a typical agent-detection assay, a sample is added to a mixture of capture antibody-coated paramagnetic beads and a Ru-conjugated detector antibody. After a short incubation period, the analyzer draws the sample into the flow cell, captures and washes the magnetic beads, and measures the electrochemiluminescent signal.
Avatar f tn nimodipine (Nimotop), felodipine (Nitrendipine, Plendil), nisoldipine (Sular), nicardipine (Cardene), verapamil (Verelan) Psychiatric medications: buspirone (BuSpar), triazolam (Halcion), carbamazepine (Tegretol), diazepam (Valium), midazolam (Versed), sertraline (Zoloft) Intestinal medications: cisapride (Propulsid) taken off the U.S.