Ezetimibe alcohol
Common Questions and Answers about Ezetimibe alcohol
zetia
d ditch it, even though moderate alcohol is generally cardioprotective for most others. I am not a low-carb dieter myself by any means, but it's uncanny how the low-fat / high-carb seems to be going wrong for you. Maybe a steak would indeed do you good. Saturated fat would also tend to raise HDL.
Did you know that the theory that keeping saturated fat and cholesterol low (to prevent artery disease) is not actually proven?
also statins like simvastatin were reported to boost response a little but better not mix 2 statins, in a report researchers of ezetimibe effect on hbv and hcv suggested the use of ezetimibe with interferon but without simvastin
ezetimibe dose is 10-20mg daily but human trials with dose 50mg daily for a limited time did not find any sides or toxicity
The FDA-approved drug ezetimibe (sold under the trade-name Zetia) is readily available and perfectly targeted to the receptor, Sainz said, so the researchers had an ideal method for testing NPC1L1's involvement in HCV infection.
The researchers showed that ezetimibe inhibited HCV infection in cell culture and in mice transplanted with human liver cells. And, unlike any currently available drugs, ezetimibe was able to inhibit infection by all six types of HCV.
You could consider going for a higher dose of Lipitor, another way to go is to consider taking a drug that limits cholesterol absorption such as Ezetimibe. There is a combination drug Simvastatin and ezetimibe that may be better in controlling cholesterol. Discuss these drugs with your doctor.
Best of luck to you. Stay positive.
A recent paper studied the effect of most FDA approved drugs on the inhibition of NTCP, the now known entry receptor for HBV. Ezetimibe was found to have a 50%inhibition conc of 25micromolar, while irbesartan, a commonly used angiotensin inhibitor to reduce blood pressure, was found to inhibit at 11.9 micromolar. Both compounds have similar MW, but irbesartan is given at up to 300mg per day, while exetimibe is dosed at 10mg.
no study for its activity on hbv, we do know it has activity but the trial has never started
simvastatin lowers hcc 50% and prevents fibrosis/cirrhosis so it is indicated on all hbver, this has thousands of pateints studied for decades to find this data on hcc
you better use simvastatin instead other statins, also ezetimibe has in vitro effect on hbv so these are the best choices on hbvers
Markers for liver damage were down as well, which suggests the compound may also have the potential to treat alcohol-related fatty liver damage.
The first author of the study, “A Liver Selective LXR Inverse Agonist that Suppresses Hepatic Steatosis” is Kristine Griffett of TSRI. Other authors include Laura A. Solt, Bahaa El-Dien M. El‐Gendy and Theodore M. Kamenecka, also of TSRI. For more information on the paper, see http://pubs.acs.org/doi/abs/10.
There was an in vitro study on ezetimibe inhibiting HBV DNA production. The ed50 was fairly low and in a similar range as lamuvidine. So it looked very interesting. But in an in vitro study you have a constant exposure to the drug, which is impossible to achieve in vivo. And the cells used are not the same as regular hepatocytes in human liver, with many differences in gene expression and cellular physiology.
About two years ago my doctor added ezetimibe to my regimen. It has been lowering my bad cholesterol how ever the first of this month I missed taking them for about a week and for the first time in years I felt less fatigued. I do have Fibromyalgia which is usually the cause of my fatigue, but this is a different type of fatigue. I have not restarted either of the cholesterol meds back because I have felt so much better. I know I need to talk to my doctor about it.
There is still much debate over the interaction of high TGL's and heart disease, no one is quite sure of the role TGLs play yet. When you speak of people with high TGL levels, some can be well into the thousands.
TGL's are easy to lower, the fastest way is to cut out empty carbs like sugars, breads and pasta. All these metabolize to sugar and raise TGL. Also, don't drink as alcohol also metabolizes as sugars and will increase serum levels of TGL.
I had very high cholesterol, due to familial hypercholesterolemia, and living on just salad for weeks did nothing for the levels. Statins have worked wonders in bringing the levels down but I also take Ezetimibe which slows absorption of fats through the gut lining. Now I can basically eat what I want and my cholesterol levels are always within the range required.
Cholesterol in the blood is not the cause of disease, it's like a side effect from the initial problem.
My latest numbers are T-343, Tri-171, DLDL-212, Direct HDL- 104. I do not have HBP, diabetes and do not smoke or drink alcohol. My diet is good but I do not exercise. It has been suggested that I could try Pravastatin as a last resort but if adverse symptoms occur, that will be the end of the statins for me. Should I even consider another statin as they all seem to have the same effects.
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