In fact, Meridia, a
weight-
loss drug, is an SNRI. Another SNRI, Effexor, has no
weight-
loss properties, but it is an antidepressant. This shows that tiny changes in chemical structure can have big effects on the brain.
I take Wellbutrin which is a SNRI, I have no loss of sex drive what so ever, and while I have put on weight I don't think it is related to the drug. I think it is related to my eating habits in that I eat crap all the time and need to knock that out of my diet.