If your mother is willing, she may want to go to a competent psychiatrist to be evaluated to see what is wrong.
Natural things that may or may not help your mother- soy milk (
natural estrogen type action), sam-E (naturemade brand), which a psychiatrist told me is a natural seratonin pill, walnuts, macadamia nuts, flaxseed oil or fish oil capsules, and freshwater fish, such as salmon (sources of omega fatty acids which can help mood. I hope your mom gets the help she needs soon.