pre-menstrual syndrome, no menstrual period during and after estrogen use, enlargement of uterine fibroids, vaginal infection with Candida, a cystitis-like syndrome, mild diarrhea, jaundice or yellowing of the skin or whites of the eyes, rash
, loss of scalp hair, and
development of new hairy areas. Lesions of the eye and
contact-lens intolerance have also been associated with estrogen therapy.