Estragel, Estradot, Tri-Est, Bi-Est) acts just like the estradiol
our ovaries secrete into the bloodstream. However, bioidentical estradiol
in pill form (brand names: Estrace, Tri-Est, Bi-Est) has the negative effect of increasing blood clots because it is not natural for estrogen to enter the bloodstream through the stomach. Pill estrogen, even if it is bio-identical, goes from the stomach to the liver and stimulates it to make clotting factors"
I will check Uzzi's book tonight.