I use what some consider a high dose of Estradiol (Vivelle Patch) and I use it to make sure my serum (NOT saliva) blood tests show I am in a range that if I had a period would put me at about day one
or day two of my cycle. I want enough
estradiol in me to make sure I can string a sentence together, avoid depression, have a sex drive, have better word retrival, have strong bones, less moodiness, have good heart function, no cramping in legs (the worst when I am low in my estradiol)...