Estradiol hormone
Common Questions and Answers about Estradiol hormone
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I am a 25 year old female, I had a saliva hormone kit evaluated with testosterone, DHEA, estradiol, and progesterone, also progesterone/estradiol ratio done. The results came back as this,
Estradiol- normal
Progesterone- Low; 47.2 (range of 127-446)
Ratio of Progesterone to estradiol - 33.0 Low; (range of 200-600)
Testosterone- 83.5 High; (range of 6.0-49)
DHEA- 366.7 High- (range of 106-300)
I can tell that i have way higher 'male hormones' than the women's hormones but, why?
I am 53 and have been in menopause for over a year. No oeriod in 10 months. I have recently gained about 8 pounds in the last two months, change in bowel habits, sore breasts. Just been feeling that my period is coming but it doesn't. Called my doctor to check my hormone levels. My estradiol went from less then 15 to 454. Not on any hormone therapy except for OTC Estroven. Hot flashes have stopped maybe because my estrogen has gone nuclear.
I am a healthly 41 year old male. My primary care doctor believes in checking hormone levels as a matter of routine. That is, she checked my hormone levels merely as a part of my annual pyshical. All serum levels in my basic chemistry panel, CBC plus differential, thyroid panel, and urine analysis were normal except my estradiol. It was 84 with a lab range with an upper limit of 54. My testosterone was normal at 630 and my DHEA was normal at 265.
My husband and I are TTC our 2nd baby. No luck for 6 months. I had hormone blood work testing on Day 2 of my period. Tested for FSH, Estradiol, Progesterone, Prolactin, and TSH. I need help understanding the implications of my results which I think indicate an imbalance. I do not have a doctor yet, I just had the test done and sent to me. I need to know what these #s mean, in terms of our odds for conceiving/treatments. Please respond if you have any info. Thanks.
Dhea(NL) 458ng/DL Ref range142-1410
Testosterone, total (DSL) 346Ng/DL Ref range 190-1037
Estradiol (DSL) 32 PG/ML None given
Cortisol 14.8 Ug/DL None given
The doctor told me the numbers were in normal range and it is not a problem. I know that my testosterone is low for my age. I plan on losing excess weight and see what happens from there.
I want enough estradiol in me to make sure I can string a sentence together, avoid depression, have a sex drive, have better word retrival, have strong bones, less moodiness, have good heart function, no cramping in legs (the worst when I am low in my estradiol)... no foot problems (yes... when estradiol was too low for a few years...bad doc's advice... yuk,... I ended up having to have surgery on both feet).. no joint pain... I could go on and on and on.
FSH enter the blood circulation and stimulates the ovary to release Estradiol (E2)
So this pathway explains at least in part the low Estradiol, but the interesting observation is the continuous feedback loop- at the end of this pathway where Estradiol turns off the release of gonadotropin-releasing hormone when it reaches the hypothalamus, in order to start the Estradiol
release cycle all over again!
I have sypmtoms of hypothyroid, adrenal and hormone imbalances. I had a hormone panel done in Oct. 07 the results where Low out of range estradiol .7, okay progesterone 135, okay ratio 193, Low testosterone 4.9, low DHEAS 4.9, okay morning cortisol 6.7. I retook the panel and added the complete cortisol work up 7/29/08 results are 1.7 estradiol, 107 progesterone, 63 ratio, 24 testosterone, 7.0 DHEAS, very low am cortisol 2.8, noon 2.2, evening 1.3, night .5.
To the point now where these symptoms are all the time now not just the two weeks before my period. I have sypmtoms of hypothyroid, adrenal and hormone imbalances. I had a hormone panel done in Oct. 07 the results where Low out of range estradiol .7, okay progesterone 135, okay ratio 193, Low testosterone 4.9, low DHEAS 4.9, okay morning cortisol 6.7. I retook the panel and added the complete cortisol work up 7/29/08 results are 1.7 estradiol, 107 progesterone, 63 ratio, 24 testosterone, 7.
Is TSH the only thyroid related test that was done? TSH is a pituitary hormone, not a thyroid hormone, so doesn't necessarily correlate with actual thyroid status. What about Free T4 and Free T3 (actual thyroid hormones)? If those were done, as well, please post their results and reference ranges so we can see where they fall within their ranges.
Do you take all of the NP at the time? What time of day do you take it?
Ranges can vary a bit by lab. However, they should not be radically different. Estradiol, estrone, and estriol are forms of estrogen with estradiol and estrone being the primary (and maybe only) systemic forms of estrogen. My lab's ranges show a max non-pregnancy and non-menopausal value of estradiol to be 498 pg/mL and estrone 268 pg/mL. Estradiol can exceed 4300 in the first trimester of pregnancy. And post-menopausal levels are less than 54 and less than 65, respectively.
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