Enbrel long term side effects

Common Questions and Answers about Enbrel long term side effects


I got my shipment this week but am waiting till Sat. night to do it in case of any <span style = 'background-color: #dae8f4'>side</span> <span style = 'background-color: #dae8f4'>effects</span>. Your experience will help me alot. I'm also going thru some tests to see if I have MS. The neuro said it was ok to start to taking the enbrel, hope he's right! Do you use the sure click injector or an actual syringe? This sounds like a stupid question but has it helped you significantly?
You are not alone, I too suffer from extreme exhaustion and lots of <span style = 'background-color: #dae8f4'>long</span> <span style = 'background-color: #dae8f4'>term</span> <span style = 'background-color: #dae8f4'>side</span> <span style = 'background-color: #dae8f4'>effects</span>. I agree that it's hard to fight the system but you have to keep trying! Keep checking with different doctors...........at least that's what I'm doing, it just is NOT normal for an HCV SVR to experience this much fatigue (there must be something else wrong). You sound like a very caring man and she is lucky to have you. My best to you and your wife.
i want to know whether to take interferon or not my pcr 600000 normal liver enzymes liver biopsy 4/6 plz tell me take it or not.
However, I have found that to varying degrees Remicade and Humira give me the following <span style = 'background-color: #dae8f4'>side</span> <span style = 'background-color: #dae8f4'>effects</span>. I am trying to find out if these are normal <span style = 'background-color: #dae8f4'>side</span> <span style = 'background-color: #dae8f4'>effects</span> and if anyone has found a way to manage them. Physical therapy is not giving me enough relief at this point.
Used in = Autoimmune diseases, Cancer therapy (Lymphomas,Leukemias) Please find my answers below. 1) <span style = 'background-color: #dae8f4'>side</span> <span style = 'background-color: #dae8f4'>effects</span>/<span style = 'background-color: #dae8f4'>long</span> <span style = 'background-color: #dae8f4'>term</span> <span style = 'background-color: #dae8f4'>effects</span> - Simple <span style = 'background-color: #dae8f4'>effects</span> like nausea,vomiting,rashes,intolerence.Severe effects like Cardiac arrest, Renal Failure, Infections,Lung Toxicity, Liver failure/inflamation. 2) Success Rate = FDA approved drug with Methotrexate for treating RA (especially refractive RA).
My main reasons for the delay are first that I don't like the idea of injections - I do fear <span style = 'background-color: #dae8f4'>long</span> <span style = 'background-color: #dae8f4'>term</span> <span style = 'background-color: #dae8f4'>side</span> <span style = 'background-color: #dae8f4'>effects</span>, and second, because of the headaches. I never had regular headaches before taking enbrel. But I have been diagnosed with migraines. They are not always severe but headache pain is just awful. I have used tylenol, advil, caffeine (coffee), and Butalbital (by prescription), with varying results. I avoid taking them if possible but when the pain is severe I must.
I did naturopathic stuff, which made me healthier, and prepared myself and my work place for when I did decide to start...Even knowing all the horrible <span style = 'background-color: #dae8f4'>long</span> <span style = 'background-color: #dae8f4'>term</span> <span style = 'background-color: #dae8f4'>effects</span>, I decided to go ahead...I had minor liver damage, my enzymes were stable, and I'd had two friends die from complications of hep c/ liver failure...and I didn't want to chance the damage getting that far...I want to be able to enjoy my grandbabies if my daughter blesses me with any...
Hi Dear enbrel (Etanercept) is an immunomodulator effective in the treatment of ankylosing spondylitis. Since it modifies the immuni system, there are a lot of <span style = 'background-color: #dae8f4'>side</span> <span style = 'background-color: #dae8f4'>effects</span> associated with it including chest pain, stomach pain, trouble breathing, mental/mood changes, severe headache, signs of infections (e.g., persistent sore throat, fever), etc. Since you are suffering from chronic sore throat, there is a possibility that it is due to etanercept.
Personally I'd rather feel as well as I can and live as pain free as possible for as <span style = 'background-color: #dae8f4'>long</span> as possible - will there be <span style = 'background-color: #dae8f4'>long</span> <span style = 'background-color: #dae8f4'>term</span> consequences down the road? Maybe, maybe not, but I don't let fear ruin what quality of life I can have right now. The drugs that seem to lose effectiveness seem to be the newer biologics like enbrel, Humira, Remicade.
The arthritis seemed to come back with a real vengence, but I just began to read some things about <span style = 'background-color: #dae8f4'>enbrel</span> I didn't like. Mainly that the <span style = 'background-color: #dae8f4'>long</span> <span style = 'background-color: #dae8f4'>term</span> <span style = 'background-color: #dae8f4'>side</span> <span style = 'background-color: #dae8f4'>effects</span> weren't really known and I didn't like that. Since August I haven't been using anything and it's really starting to wear on me. I did try the Humara for a few months, but it didn't do anything for me, and the shot hurt like hell..............
I have now been through prednisone, methotrexate, <span style = 'background-color: #dae8f4'>enbrel</span>, Humara(Humira? sp) then back to <span style = 'background-color: #dae8f4'>enbrel</span>.......then nothing. The <span style = 'background-color: #dae8f4'>enbrel</span> worked very well, but I have massive anxiety about the biologics. I just don't trust them and and it's very frustrating. I feel like I'm between a rock and a hard spot. On one hand they really do make me feel better, pain and ROM vastly improved.
It can give you short-<span style = 'background-color: #dae8f4'>term</span> relief but trust me, the <span style = 'background-color: #dae8f4'>long</span>-<span style = 'background-color: #dae8f4'>term</span> <span style = 'background-color: #dae8f4'>effects</span> of prednisone are not worth it. I don't have your chronic fatigue issues, but I can see where mtx can contribute to that problem! I assume you are taking a prescription folic acid tablet 24 hours after your mtx dose? This can help alleviate some of the unpleasant side effects like mouth sores and hair thinning.
She did not think it was hmira but who knows with me, I get a lot of upper thigh muscle burning pain after hte shot for about 6 days too that keeps me awake I worry about <span style = 'background-color: #dae8f4'>long</span> <span style = 'background-color: #dae8f4'>term</span> <span style = 'background-color: #dae8f4'>effects</span>. I took <span style = 'background-color: #dae8f4'>enbrel</span> for over 10 years and did not have any problems with it so who knows with me. Thanks for the reply and appreciate anymore advice you have.
Hi there, I just want to tell you that with early and aggressive treatment, your disease doesn't necessarily have to get significantly worse. Placquenil and methotrexate (mtx) are to of the first, go-to, baseline meds they almost always try. I've been on mtx for decades and it's been my mainstay. Both meds have been around for a long, long time and their efficacy and side effects are well known and documented.
February 10, 2009 - OMG - I can't freaking believe it - yep SVR - I was feeling pretty bad and it had been 5 months since I had my 2 mo post PCR which was clear and I knew I could not treat again due to the awful <span style = 'background-color: #dae8f4'>side</span> <span style = 'background-color: #dae8f4'>effects</span> and I just didn't want to know - but I finally gave in and tested and just found out I'm SVR. I had only treated for 13 weeks (am a 2b) and most of it was at very reduced doses - so it's pretty much a miracle - I have my life back - wow...
Weight gain is the least of your worries with prednisone! Please, please stay away from this stuff if you can. The <span style = 'background-color: #dae8f4'>long</span>-<span style = 'background-color: #dae8f4'>term</span> <span style = 'background-color: #dae8f4'>side</span> <span style = 'background-color: #dae8f4'>effects</span> of using bursts of it off and on, aren't worth it. It can cause avascular necrosis (bone death) in your major joints like hips and shoulders, osteoporosis, sleep problems, the list goes on. Unless you absolutely can't function without it, try to avoid it. And for the record, you're not a whiner.
I am a <span style = 'background-color: #dae8f4'>long</span> <span style = 'background-color: #dae8f4'>term</span> RA patient who is now seeing a pulmonologist for shortness of breath. All cardiac tests were normal. Several ground glass opacities in my right lung showed up on a CT scan in July 2011. enbrel was discontinued and coincidentally I took a regime of prednisone for an allergy problem - 60 mg for one week, then with a weekly taper.
everywhere!! Unfortunately the <span style = 'background-color: #dae8f4'>side</span> <span style = 'background-color: #dae8f4'>effects</span> are too risky to even consider taking Prednisone <span style = 'background-color: #dae8f4'>long</span> <span style = 'background-color: #dae8f4'>term</span>. It has been know to destroy bones and joints (among other things) which only will add to your pain.... and then you can never have the short term pain relief that is obtained from a burst of steroids. Most physicians will not prescribe a steroid more then twice a year ... some physicians will not even order it that often. I know that nerve pain is very difficult to treat.
I was taking Arava for MCTD before I got pregnant. I had decent success with it, and no <span style = 'background-color: #dae8f4'>side</span> <span style = 'background-color: #dae8f4'>effects</span>. Theat Dr. is very unprofessional to argue with you like that. You have every right to get a 2nd opinion, and to go to a neurologist. The numbness, tingling, and weakness may be neurological, but can be conected to some autoimmune disorders as well. Good luck.
The new findings should reassure patients, but questions remain about the short-<span style = 'background-color: #dae8f4'>term</span> and <span style = 'background-color: #dae8f4'>long</span>-<span style = 'background-color: #dae8f4'>term</span> safety of TNF-blocking drugs, rheumatologist Eric Matteson, MD, of Mayo Clinic in Rochester, Minn., tells WebMD. The Swedish researchers found no difference in cancer risk among rheumatoid arthritis patients who did and did not take the drugs over six years of follow-up.
I hear you about the <span style = 'background-color: #dae8f4'>long</span>-<span style = 'background-color: #dae8f4'>term</span> <span style = 'background-color: #dae8f4'>side</span> <span style = 'background-color: #dae8f4'>effects</span>. I've been on Fosamax for my bones for many years and only recently learned that long term use of it can make one's bones brittle. Niiiice. Like the old saying goes, "Ya pays your money and ya takes your chances." :) Still, overall I think I've done well. You make the best decision for you with the information you have at the time. Hopefully someone who's had experience with Humira will chime in here.
I was diagnosed with psoriatic arthritis when I was 18 years old. I'm 62 now. Over the years I have been on probably everything out there, starting with gold treatments back in the early 70's. Because there wasn't much available back then, I ate aspirin like candy which helped at that time, but blew out my stomach. Then came ibuprophene and it's clones and I began taking them. I can't anymore.
don't ask me why and how I got into reading this stuff, i guess my post to couch yesterday got me into trying to remember the name of a disorder, plus all of us complaining of RA, fibromyalgia and other neuropathies, that can't be explained by tx sides alone and those left with <span style = 'background-color: #dae8f4'>long</span> <span style = 'background-color: #dae8f4'>term</span> <span style = 'background-color: #dae8f4'>effects</span>...led me to this. first, i started with the disorder:Reiter's syndrome, it took me to HLA-B27 and so on. while reading it something kept clicking about these two and possible relation to hcv symptoms...
Because your immune system is going haywire, it's common to have swollen lymph nodes as you describe - along with severe fatigue, flu-like symptoms, skin issues, dry mouth/eyes. Steroids help in the short <span style = 'background-color: #dae8f4'>term</span>, but it is best to stay off these if at all possible. The <span style = 'background-color: #dae8f4'>long</span>-term affects are not worth it, IMO. There are all kinds of new medications out there now, so I'm confused as to why these haven't been tried.
In a word, YES. Start treatment to get on top of this before it starts manifesting in other joints (trust me, it will) plus causing further damage to your hands. It's not just stiffness, pain and swelling, it's real damage being done to your joints that will eventually lead to joint deformity and extremely limited ability to use your hands at all. The purpose of the stronger drugs is to prevent this from happening; to slow down or hopefully halt the progression of the disease.
I feel that if I do not at least try the methotrexate that he will not be able to diagnose me correctly. But I really worry about the <span style = 'background-color: #dae8f4'>long</span> <span style = 'background-color: #dae8f4'>term</span> <span style = 'background-color: #dae8f4'>side</span> <span style = 'background-color: #dae8f4'>effects</span> of this drug. It seems as though there is no "perfect" treatment and many unknowns about these diseases and everything is trial and error and symptom based. I will definately check into the folic acid. Thanks again!
My one word of caution is not to let them just give you prednisone - it can seem like a miracle drug but the <span style = 'background-color: #dae8f4'>long</span> <span style = 'background-color: #dae8f4'>term</span> <span style = 'background-color: #dae8f4'>side</span> <span style = 'background-color: #dae8f4'>effects</span> can be severe. It's all right to use as a tool to get you through until the more effective drugs kick in, but not by itself. As for diet, there is no official arthritis diet, however it won't hurt to try different things to see if certain foods make you feel worse. There is such a thing called an "anti-inflammatory diet" but I hadn't tried it.
You're on a pretty low dose of prednisone, but keep an eye on that bone density and watch for other <span style = 'background-color: #dae8f4'>long</span> <span style = 'background-color: #dae8f4'>term</span> <span style = 'background-color: #dae8f4'>side</span> <span style = 'background-color: #dae8f4'>effects</span>, as well. If you can possibly wean of it completely as you find a better combination of meds, please do. It's best not to take it long term. Hope this helps!
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