Enbrel for crohn's disease

Common Questions and Answers about Enbrel for crohn's disease


Today I am recovering from a ruptured bowel, I once again have an iliostomy, and have been diagonsed with Crohn's disease. The first line of treatment was 4 weeks on Pentasa and Rowasa. Following a scope last week, the crohn's is clear in the small intestine and I am feeling pretty good. (still 30 lbs underweight). However, the j-pouch is still inflamed. What treatments have been successful? My doctor is discussing enbrel, humara, injections to try to save the pouch.
The TNF Blockers work really well for the reactive arthritis related to my Crohn's Disease [Crohn's Colitis]. However, I have found that to varying degrees Remicade and Humira give me the following side effects. I am trying to find out if these are normal side effects and if anyone has found a way to manage them. Physical therapy is not giving me enough relief at this point.
The pain often would land me in the ER where I would usually get a CT scan because the ER Doctors thought I was either passing a kidney stone or having acute appendicitis. My doctors suspicioned that I had Crohn's and tested me for it. I had the IBD first step, but that came out negative. I then had a colonoscopy and barium enema and swallow. Nothing showed. When I had my EGD, however, it turned out there was some chronic inflammation present.
I was put on Humira last year for a 6 month trial for my Crohn's Disease. It worked great for my Crohn's, but after being on it for 6 months, I suddenly developed a Severe Chronic Daily Headache problem. The pain manifests itself over my brow, and raidiates back to the base of my neck. There is pressure as well, as though my head is in a vise. I never used to get headaches, at all, but am now living with these debilitating headaches.
My son, age 24, is taking Humira for his Crohn's Disease and Ulcerative Colitis. He gives himself the shot every 2 weeks, but within 24 hours, he has a excruciating migraine for 5 days. He is on morphine and fentanyl and it doesn't even touch the pain. The Humira has kept him in remission for 4 years, so we don't want to go off of it, but I worry about what it is doing to his mind/body/spirit!
There is a lot of inter-connectivity in auto-immune diseases. Crohn's, Colitis and RA are all auto-immune. Some arthritis type auto-immune diseases can have gastro-intestinal impacts - Lupus is one. As well, I do know that colitis can be associated with ankylosing spondylitis (spinal arthritis that begins with sacral region pain). I believe there are other arthritis conditions that can be related to Crohn's and Colitis.
Hi - I have had Crohn's disease for 34 yrs and have been on methotrexate (self inject 12.5 mg weekly) for 6 years, with a short break when having FEC chemo for breast cancer. I have monthly blood tests including liver function and everything has been okay until last month when my red cells were enlarged and white cells low. Gastro is keeping an eye on them, but has continued to prescribe it.
I have done specific research on Biologics, including Enbrel and Humira, and have put together an alternate all natural protocol, that targets Tumor Necrosis Factor Alpha (TNFa) one of the main culprits in inflammatory processes, leading to rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, moderate to severe chronic psoriasis and juvenile idiopathic arthritis and other conditions, but without any great associated costs (biologics can cost
There are lots of new and exciting treatments available now for Crohn's. Remicade and Enbrel are proving to be very effective in forcing and keeping the disease in remission. Ask about these drugs at your appointment. Again, good luck to you.
Research is assessing possible relationship between HS and Hashimoto's thyroiditis (the most common cause of hypothyroidism in the developed world), Crohn's disease, rheumatoid arthritis, and squamous cell carcinoma. To date, the genes known to be contributing to autoimmune thyroid disease (Hashimoto's thyroiditis and Graves' disease) fall into two categories: immune regulatory genes (including HLA, CTLA4, PTPN22, CD40, CD25, and FCRL3) and thyroid-specific genes (TG and TSHR).
There have been x-rays, MRIs, bone scan, bone marrow biopsy, countless blood tests (including a genetic test indicating increased likelihood of Crohn's disease), numerous medications tried, etc. I have a relative with spondylitis and a sibling with rheumatoid arthritis but I do not have any of the common indicators. The chest pain and eye inflammation seem to be unique to me among my family.
Very frustrating! Has anyone been test for celiac disease? I have had that for most of my life and now they are telling me that it my be part of that. Otherwise they are thinking Crohn's, which takes 7 years to show up in any tests. Anyone been tested for that? Also get your Vitamin D checked. Mine was very very low! I have been to a neurologist, rhuematologist and infectious disease doctor (to rule out lyme disease). I tried to get into Mayo clinic to get answers.
The black box warnings for prescriptions for the treatment of rheumatoid arthritis, psoriatic arthritis and Crohn's Disease are required because of an increased risk of lymphoma and other malignancies. These medications include Remicade, Enbrel, Humira and Symponi. The FDA issued an update on 4/15/11 for long-acting beta agonists (LABAs) for the treatment of asthma.
The water sensation eventually went away after a year or two, but after taking a month of antibiotics 4 years later for a possible case of lyme disease causing the chronic myalgia the water sensations started to appear randomly like water drops everywhere. I took the antibiotics for 6 months and stoped, but the water sensations have only increased. I'm going to getting a small fiber nerve sample test. The months and year prior to the water sensation I started allergy shots, but stopped.
No side effects, and costs only $30 per month without health insurance - the only possible downside is that it may not cure your incurable disease. People are using it for cancer, Crohn's, MS, fibromyalgia, autism, and all other autoimmune diseases. For hep c LDN will not eradicate the virus, but it will reduce the viral load levels and inflammation drastically and keep them there. Meanwhile, many naturopaths do the IV lipoic acid treatments - they do not have to be MDs to do so.
If it's an allergy (for me) I think it might be to MSG, if it's an intolerance (again for me) at the moment I'm thinking it's to very fatty foods. It's always worse when I'm stressing about something. Does any of that apply to you? You can get IBS tabs over the counter (we can here in UK anyway). Or you might want to try testing out foods to see if you are allergic/intolerant. It's a pain to do this (I keep meaning to, but haven't yet).
Well, I found out that the reason for my itch was thyroid disease. It's called cold Urticaria. Thyroid disease can cause sensitivity to cold or hot. In our case, it's cold. So, get a blood test, and make an appointment with the endocrinologist.
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