I have never weaned off effexor
but went from effexor
to Cymbalta one time and
did not have a withdrawal. Once I went "cold turkey" off effexor and
it was brutal. I was disoriented, depressed, suicidal, headaches, brain zaps, nauseated and
finally went into a mixed episode of my Bipolar shortly after. I would not ever suggest that! I am back on effexor
now with other medications. effexor
XR is the only antidepressant I have found that helps me. I beleive it takes a good 2 wks.