Yup there are studies out now that are proving that the ssri/snri meds can't be used long term like MS's or maoi's. So these meds aren't the wonder drugs they were touted to be. I think the those drugs are great for situational depression, like a family death, losing a job, traumatic events which have triggered depression, but long term treatement as a stand alone drug, I dare say they don't. I've been on Luvox, Zoloft, Welbutrin, Effexor, Celexa, Cipralex and Cymbalta.