Efavirenz teratogenicity

Common Questions and Answers about Efavirenz teratogenicity

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Avatar n tn Are there still any evidence of efavirenz teratogenicity in human studies especially on the neuro tube defect
Avatar m tn I have 20 years and I have HIV positive person. I drink medicines already 4 months. I use drugs Truvada and Efavirenz Teva. Please tell me how to code your disease treated? Whether you are at injection instead of pills?
Avatar n tn Animal studies have revealed evidence of teratogenicity when epinephrine was given in doses approximately 25 times the usual recommended human dose (on a per kg basis). There are no reports of teratogenicity in humans. There are no controlled data in human pregnancy. Epinephrine is only recommended for use during pregnancy when benefit outweighs risk.
Avatar f tn 1 hours ago I had protected sex with a sex worker which ended with a failed condom(punched) and then hour later i went to consult doctor and he prescribed EFAVIRENZ and LAMZID.AM I STIL SAFE?
Avatar m tn Since that time, he is receiving HAART with lamivudine-zidovudine-efavirenz twice daily, but he told me that there are some days ( at maximun 3) that he does not take the pills, but most days of the month he is adhering to the treatment. His current viral load is 39,000 copies/ml. When I realized of him diagnosis, I went to a doctor who gave me profilaxis about 18 hours post-exposure with lamivudine-zidovudine.
Avatar f tn Hello doctor I am very confused now because after 2 years my wife got conceived(one month) but instead of happy I am worrying because she had taken albendazole 400 mg 2 weeks before , I come across about embryo toxicity and teratogenicity of albendazole ... Now am worried very much about my baby ...
Avatar n tn _____________ Animal studies have failed to reveal evidence of teratogenicity or fetotoxicity. There are no controlled data in human pregnancy. Methyldopa is only recommended for use during pregnancy when benefit outweighs risk. Methyldopa crosses the placenta, and may cause mild hypotension in neonates of treated mothers.
Avatar f tn At present, metformin is classified as Class B in pregnancy, with no evidence of animal or fetal toxicity or teratogenicity. 5] Reproduction studies in rats and rabbits show no teratogenicity with dosages up to 600 mg/kg per day, approximately twice the recommended human dosage.[6] Additionally, there are numerous reports using metformin for the treatment of gestational diabetes mellitus (GDM), without evidence of fetal harm.
Avatar n tn I am an HIV + male. 43 on truvada/ efavirenz for 2 year with a count of minus 20(undetectable). I was penetrated twice last week where the condom broke and was NOT replaced. The "top" partner is aware of my hiv status. What are the chances of infection for him and apart from testing what should be done? I am otherwise very healthy, no cuts, blood or aparent bruising was detected. I am freaking out for him.
Avatar f tn My doctor recently put me on a combination of drugs for PEP, the drugs are lamzid and efavirenz and have very serious side effects. My exposure was licking/sucking a nipple of a non-pregnant HIV positive person. No milk came or blood came out but just had an after taste in my mouth. The act was for 2-3 seconds. What are my chances of getting HIV and are the reported cases of infection in adults, cause I know with babies you can.
Avatar n tn Animal and human data have revealed evidence of embryolethality and teratogenicity associated with angiotensin converting enzyme (ACE) inhibitors. There are no controlled data in human pregnancy. Congenital malformations have been reported with the use of ACE inhibitors during the first trimester of pregnancy, while fetal and neonatal toxicity, death, and congenital anomalies have been reported with the use of ACE inhibitors during the second and third trimesters of pregnancy.
Avatar m tn Welcome to the forum. Thanks for your question. Since you are under care with PEP drugs, that doctor or clinic really ought to be the primary source of information about your risk, follow-up plans, etc. Therefore, my comments are brief. Based on HIV infected persons' sexual histories of when and how they were infected, a CDC study calculated a risk of 1 HIV infection for every 10,000 episodes or performing fellatio on infected partners.
181575 tn?1250198786 Someone asked me about Atripla today. I figure I put my comments here. Atripla is a drug used to treat HIV. It actually consists of 3 drugs, emtricitabine and tenofovir (which also works against HBV) and efavirenz (doesn't work against HBV). Combination treatment is common practice for HIV so they combine multiple drugs into 1 pill. Of course Atripla is NOT an FDA approved therapy for HBV.
Avatar m tn m now under retro-viral treatment (Abacavir, 3TC Lamiduvina, and Efavirenz TM as known in my country), healthy, fit, high CD4 count, undetectable viral load. Recently, I met a person, we kissed and we practiced oral sex on each other. Eventhough I know my condition, and have always tried to avoid people practice fellation on me, he insisted and at the end I agreed. Now, I am really concerned about him. Could he have been infected? Should I tell him to test for HIV?
863555 tn?1239133228 Before, instead of lopinarvir/retonavir I used efavirenz, which made me high. Nice for party or sex, but otherwise pretty annoying. It turned out my HIV is resistant to efavirenz.
Avatar m tn Also suffering from Hypothyroidism (Thyroxine 100 mg/day). Possibility of anti-conversant induced teratogenicity is there. 5. Blood group : Mother B+, Father : O+ 6. Suggested for Amniocentesis & Abortion by Dr. Madhulika Kabra (HOD, Genetics, AIIMS) & Dr. I. C. Verma (HOD Genetics, Sir Ganga Ram Hospital). As per them, the Binder Syndrome is due to intake of Carbamazepine.
Avatar f tn Hi all, I have been on a combination of PEP drugs for the past week, the drugs are lamzid and efavirenz. 2 days after taking the drugs I started growing ulcers on my mouth (which has happened before) and I think one in my anus. Could this mean that I am HIV positive? I am very scared. My exposure was sucking a nipple of a woman for less than 2 seconds.
Avatar m tn On AUGUST 19TH and AUGUST 20TH, I started taking ARVs which doctor prescribed. (Tenofovir disoproxil fumarate 300mg, Lamivudine USP 600mg, Efavirenz USP 200mg). ARVs made me dizzy, so I stoppped on AUGUST 21ST and AUGUST 22ND. After the viral load result, I started ARVs again. One pill everyday regularly. 4. On AUGUST 29th, I gave blood sample for PCR-HIV QUALITATIVE: (Performed using the Roche COBAS Ampliprep/COBAS Taqman HIV-1 Qualitative Version 2.0 assay.) It turned out negative.
Avatar m tn Quite so.There are quite a few side-effects like teratogenicity which occuopies the scientific mind more than these leeser known!
Avatar f tn I was given pep (efavirenz+ tenofovir + lamivudine) for 28 days after 48 hours. But I had it for 29 days instead. Now after 57 days I am having flu like symptoms. Runny nose and a bit of sore throat. No fever though. And my abdominal hurts a bit and a little joint pain.. 1. What are my chances of contracting hiv from this fingering exposure? 2. Is pep successful if taken at 48 hours of exposure.? 3. Do i need testing? I was tested negative at baseline.
Avatar m tn They took my blood test only as a ground zero (for later comparisons). Then doctor prescribed me Zilarvir (2 tablets a day) and Efavirenz (1 tablet a day) to take them one (1) month. The medicines arrived at 15:00 (3:00 PM) and I took both - 17 hours after the incident and high risk exposure. Doctor told me to come after one month when they will take a new blood test and follow-up.
Avatar f tn I am on 300 mg of lamivudine (1 time before bed) 600 mg of efavirenz (1 time before bed) and 300 mg tenofovir (1 time before bed), How effective this for PEP? I am not sure coz I went for an emergency ward which may not have expert on HIV infection. Also I read the label it said for PEP purpouse lamivudine should be used as 150 mg twice daily. Am I right?
Avatar m tn After 29 hours of exposure, I took Zifam Eletec (Tenofovir Disoproxil Fumarate 300mg+Lamivudine 300mg+Efavirenz 600mg) and I had been taking it regularly at the same exact time every day (30 days course) which ended on Jan 27, 2022. 1. For my case, may I know the HIV infection risk/possibility for my exposure (because the HIV status of that female is unknown and contact time is short)? 2.
Avatar f tn As my husband and I wish to have children and I ws concern about a side effects and risks been on medication the doctor said that although Cabergoline has not been demonstrated to cause any problems with teratogenicity, Bromocriptine is often substituted as more data is available so I switched to Bromocriptine 1.25 mg for 2 weeks then increased to 2.5 mg and the doctor said that my eventual required dose may be up to 30 mg daily. On the 26.05.
Avatar m tn Nearly all animal studies have revealed evidence of embryolethality and teratogenicity. There are no controlled data in human pregnancies. One published case reports the uneventful use of ribavirin at 33 weeks gestation. Ribavirin therapy is contraindicated in women who are pregnant and in the male partners of women who are pregnant.
Avatar m tn Since that time, he is receiving HAART with lamivudine-zidovudine-efavirenz twice daily, but he told me that there are some days ( at maximun 3) that he does not take the pills, but most days of the month he is adhering to the treatment. His current viral load is 34,000 copies/ml. When I realized of him diagnosis, I went to a doctor who gave me profilaxis about 18 hours post-exposure with Combivir.
Avatar f tn As my husband and I wish to have children and I was concern about a side effects and risks been on medication the doctor said that although Cabergoline has not been demonstrated to cause any problems with teratogenicity, Bromocriptine is often substituted as more data is available so I switched to Bromocriptine 1.25 mg for 2 weeks then increased to 2.5 mg and the doctor said that my eventual required dose may be up to 30 mg daily. On the 26.05.