Efavirenz solubility
Common Questions and Answers about Efavirenz solubility
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I have 20 years and I have HIV positive person. I drink medicines already 4 months. I use drugs Truvada and Efavirenz Teva. Please tell me how to code your disease treated? Whether you are at injection instead of pills?
Are there still any evidence of efavirenz teratogenicity in human studies especially on the neuro tube defect
1 hours ago I had protected sex with a sex worker which ended with a failed condom(punched) and then hour later i went to consult doctor and he prescribed EFAVIRENZ and LAMZID.AM I STIL SAFE?
Since that time, he is receiving HAART with lamivudine-zidovudine-efavirenz twice daily, but he told me that there are some days ( at maximun 3) that he does not take the pills, but most days of the month he is adhering to the treatment. His current viral load is 39,000 copies/ml.
When I realized of him diagnosis, I went to a doctor who gave me profilaxis about 18 hours post-exposure with lamivudine-zidovudine.
I am an HIV + male. 43 on truvada/ efavirenz for 2 year with a count of minus 20(undetectable). I was penetrated twice last week where the condom broke and was NOT replaced. The "top" partner is aware of my hiv status. What are the chances of infection for him and apart from testing what should be done? I am otherwise very healthy, no cuts, blood or aparent bruising was detected. I am freaking out for him.
My doctor recently put me on a combination of drugs for PEP, the drugs are lamzid and efavirenz and have very serious side effects. My exposure was licking/sucking a nipple of a non-pregnant HIV positive person. No milk came or blood came out but just had an after taste in my mouth. The act was for 2-3 seconds. What are my chances of getting HIV and are the reported cases of infection in adults, cause I know with babies you can.
Methadone has a slow metabolism and very high fat solubility, making it longer lasting than morphine-based drugs. Methadone has a typical elimination half-life of 15 to 60 hours with an average of i would say about 22. However, metabolism rates vary greatly between individuals, up to a factor of 100 ranging from as few as 4 hours to as many as 130 hours, or even 190 hours. So it's hard to say.
The water solubility of bilirubin allows the bilirubin to be excreted into bile. (Bile then is used to digest fats.)
Total bilirubin, if I remember correctly, is the conjugated hemoglobin, since there is also another portion that is not conjugated.
What the elevated total bilirubin means at this point is 'something' is going on, but you may need more information before your doc can determine the cause.
Welcome to the forum. Thanks for your question.
Since you are under care with PEP drugs, that doctor or clinic really ought to be the primary source of information about your risk, follow-up plans, etc. Therefore, my comments are brief.
Based on HIV infected persons' sexual histories of when and how they were infected, a CDC study calculated a risk of 1 HIV infection for every 10,000 episodes or performing fellatio on infected partners.
m now under retro-viral treatment (Abacavir, 3TC Lamiduvina, and Efavirenz TM as known in my country), healthy, fit, high CD4 count, undetectable viral load. Recently, I met a person, we kissed and we practiced oral sex on each other. Eventhough I know my condition, and have always tried to avoid people practice fellation on me, he insisted and at the end I agreed. Now, I am really concerned about him. Could he have been infected? Should I tell him to test for HIV?
The main requirements for them are (1) high IFN-inducing activity, (2) absence of side effects, (3) wide spectrum of antimicrobial activity, (4) broad therapeutic security and, (5) good solubility in water and biologic liquids. IFN inducers stimulate IFN production in different cells and organs, and that determines the strategy for their application. Amixin (OOO "Lancepharm," Moscow, Russia) induces IFN-?/? production mostly in T cells. Cycloferon (NTFF "Polysan," St.
However, factors that can affect absorption include oral pH, salivary enzymes, lipid solubility, and molecular weight (molecules may be too large to pass through the mucous membranes). A sublingual product, specifically created to ensure effective absorption, is recommended.
Hi all,
I have been on a combination of PEP drugs for the past week, the drugs are lamzid and efavirenz. 2 days after taking the drugs I started growing ulcers on my mouth (which has happened before) and I think one in my anus. Could this mean that I am HIV positive? I am very scared. My exposure was sucking a nipple of a woman for less than 2 seconds.
On AUGUST 19TH and AUGUST 20TH, I started taking ARVs which doctor prescribed. (Tenofovir disoproxil fumarate 300mg, Lamivudine USP 600mg, Efavirenz USP 200mg). ARVs made me dizzy, so I stoppped on AUGUST 21ST and AUGUST 22ND. After the viral load result, I started ARVs again. One pill everyday regularly.
4. On AUGUST 29th, I gave blood sample for PCR-HIV QUALITATIVE: (Performed using the Roche COBAS Ampliprep/COBAS Taqman HIV-1 Qualitative Version 2.0 assay.) It turned out negative.
I was given pep (efavirenz+ tenofovir + lamivudine) for 28 days after 48 hours. But I had it for 29 days instead. Now after 57 days I am having flu like symptoms. Runny nose and a bit of sore throat. No fever though. And my abdominal hurts a bit and a little joint pain..
1. What are my chances of contracting hiv from this fingering exposure?
2. Is pep successful if taken at 48 hours of exposure.?
3. Do i need testing? I was tested negative at baseline.
They took my blood test only as a ground zero (for later comparisons). Then doctor prescribed me Zilarvir (2 tablets a day) and Efavirenz (1 tablet a day) to take them one (1) month. The medicines arrived at 15:00 (3:00 PM) and I took both - 17 hours after the incident and high risk exposure.
Doctor told me to come after one month when they will take a new blood test and follow-up.
I am on 300 mg of lamivudine (1 time before bed) 600 mg of efavirenz (1 time before bed) and 300 mg tenofovir (1 time before bed), How effective this for PEP? I am not sure coz I went for an emergency ward which may not have expert on HIV infection. Also I read the label it said for PEP purpouse lamivudine should be used as 150 mg twice daily. Am I right?
After 29 hours of exposure, I took Zifam Eletec (Tenofovir Disoproxil Fumarate 300mg+Lamivudine 300mg+Efavirenz 600mg) and I had been taking it regularly at the same exact time every day (30 days course) which ended on Jan 27, 2022.
1. For my case, may I know the HIV infection risk/possibility for my exposure (because the HIV status of that female is unknown and contact time is short)?
2.
Since that time, he is receiving HAART with lamivudine-zidovudine-efavirenz twice daily, but he told me that there are some days ( at maximun 3) that he does not take the pills, but most days of the month he is adhering to the treatment. His current viral load is 34,000 copies/ml.
When I realized of him diagnosis, I went to a doctor who gave me profilaxis about 18 hours post-exposure with Combivir.
(By the way, although losartan is currently being researched in Johns Hopkins clinical trials, other ARBs such as telmisartan are probably most effective given their increased lipid solubility and thus increased tissue penetration.)
I strongly encourage you to visit www.marfanlife.net and find the very lengthy thread titled "Losartan" or something to that effect. Probably some of the most important reading of your life.
the brain is affected quickly as alcohol will cross what is called the blood-brain barrier due to its solubility. this can compromise involuntary actions such as heartbeat, breathing and gag reflex. organs such as the liver and pancreas can suffer tissue destruction resulting in everything from lowered function and scarring to complete organ failure. for diagnosing existing damage, your doctor can order bloodwork including a liver panel to check things like enzyme levels.
Hello Teak,
I have a question I'd like to ask you. I engaged in protected vaginal intercourse with a CSW here in a spa in Malaysia. Unfortunately towards the end of the act, my condom broke - I must have had intercourse for about a minute or two before realising. Upon realisation, I immediately stopped intercourse and freaked out. Upon asking the CSW - she assured me that she's HIV negative and that she get's checked every six months in order to maintain employment.
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