Duloxetine and mechanism of action

Common Questions and Answers about Duloxetine and mechanism of action

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Avatar f tn , duloxetine) has a combination mechanism of action involving serotonin and norepinephrine making it useful in depression and also neuropathic pain. When a peripheral nerve is injured there is an increase in pain sensitive fibers leading to increase pain recognition. This causes a change in central (i.e., brain/spinal cord) recognition of pain. One major neurotransmitter involved in this is norepinephrine. Cymbalta works to modulate this change.
Avatar m tn I have beem taking carvedilol for three years and have never seen a description of it so concise and clear.
Avatar n tn First thing to note, Unfortunately smoking does affects the amount of duloxetine in your system and blood stream meaning that you will loose between 40 - 50% of the duloxetine dose you take. It is not uncommon for people to have their duloxetine prescription increased if they smoke.
5055866 tn?1362951481 Unfortunately smoking does affects the amount of duloxetine in your system and blood stream meaning that you will loose between 40 - 50% of the duloxetine dose you take. It is not uncommon for people to have their duloxetine prescription increased if they smoke. Unfortunately it is not uncommon if you miss a dose to be experiencing these problems if your on a high dose, my patients even at a dose of 30mg do experience brain zaps, nausea and vomiting even with just one day missed.
Avatar f tn Potassium is a chemical element and it is part of the electrolyte that should be in balance with other lytes to adequately conduct an electrical impulse that originates with the sinus node in the right atrium. The mechanism of action is not completely understood, but what is when a voltage (unit of potential for conduction) and electrolyte there will conduction and passage of electrical impluses.
Avatar m tn First thing to note, Unfortunately smoking does affects the amount of duloxetine in your system and blood stream meaning that you will loose between 40 - 50% of the duloxetine dose you take. It is not uncommon for people to have their duloxetine prescription increased if they smoke.
1218873 tn?1300091216 First thing to note, Unfortunately smoking does affects the amount of duloxetine in your system and blood stream meaning that you will loose between 40 - 50% of the duloxetine dose you take. It is not uncommon for people to have their duloxetine prescription increased if they smoke.
Avatar m tn http://www.nasdaq.
962875 tn?1314210036 This is an informational post. As many of you know or have experienced, the AIs ( Arimidex, Femara, Aromasin), which are used to treat hormone-receptor positve breast cancer, often produce joint or muscle pain as a side effect. For about 20% of women, the side effects are so severe that they stop taking their medicine, which increases the risk that their breast cancer will recur.
Avatar m tn Oyakawa I am in my 3rd year of medical school and I was wondering the mechanism of action of steroid injections in the eyelid causing cataracts. It is not an osmotic agent so why does that occur? thanks so much.
1580828 tn?1322128022 Unfortunately smoking does affects the amount of duloxetine in your system and blood stream meaning that you will loose between 40 - 50% of the duloxetine dose you take. It is not uncommon for people to have their duloxetine prescription increased if they smoke.
382218 tn?1341181487 Thanks for posting this DV. My favorite part was the mechanism of action for Tecfidera. "Poorly understood...
Avatar n tn My recommendation is to have 6 month bloods done of you kidney and liver function tests;
Avatar f tn Hello. I am miserable. First of I have fibromyalgia and POTS so I have pins and needles and burning sensations occasionally but nothing ever to this scale. This is pure torture. The pain is 24/7 non stop for the past week. My rheumatologist just prescribed me steroids and I will take them for 6 days. The first day seemed to help but today I feel like I’m back where I started and I’m immobilized by the pain. What could this be? I’m so desperate for help and answers and relief.
Avatar f tn I am taking DULOXETINE 60MG.
Avatar f tn Plavix has a unique mechanism of action by blocking the amplification of platelet activation by released ADP, and often used with aspirin to prevent the risk of clots for the first year after DES implant. Plavix and aspirin have different mechanism of action to prevent clots. After a year, plavix is usually discontinue as the risk for clots is decreased, and aspirin is continued long term. The risk of a clot is about 3%.
Avatar f tn I did take Duloxetine previously for pain (adjunct to the Celebrex) and it did help, but my GP is skeptical that Gabapentin would help even if combined with Duloxetine. Does anyone else have Osteoarthritis and is unable to take NSAIDS and have you found a medication that works? Thanks in advance for your replies.
Avatar f tn I am very sensitive to meds and the pain meds that they gave in the hospital made me sick to my stomach so I discontinued them about 18 hours after surgery and took only tylenol as needed. I have tried heat, ice and massage to get the tightness out of my neck and scapula area but this doesn't seem to help. Any suggestions and information you can give me on what to expect during my recovery would be appreciated. Thank you so much for your time.
Avatar m tn Does anyone know if alpha blockers negate the positive effects of Duloxetine? It seems that if norepinephrine is blocked via the alpha blocker than it would cancel out the effect of the norepinephrine re-uptake and subsequent positive effects of an SNRI.
Avatar f tn develops due to excessive consumption of alcohol and the other that develops in non-drinkers. It is important that food habits: lack or very low physical activity and being overweight may be modified. Take care and do keep us posted.
Avatar f tn I think my anxiety attacks are pretty much under control since I take the duloxetine, and I really think with me taking Duloxetine and me completely stopping the vyvanse was why I didn't have a harder time coming off the medication.
Avatar n tn A heart murmur is a sound heard as the blood flows through the heart and especially the blood flow through the heart valves. If there is a defect, a stethoscope hears a specific sound for different defects. ■Angiotensin-converting enzyme (ACE) inhibitors. ACE inhibitors lower the system's blood pressure. The mechanism of action is to relax the blood vessels and that provides less resistance for the heart to pump against and decreases blood pressure.
Avatar m tn So I went to counseling to try and get over this without taking medications. Well a couple of weekends ago I had a really bad weekend. I went to my doctor because I was having abdominal pains and was thinking it was something serious (which is what my anxiety problem is: health concerns). He basically said this was all anxiety still, and thought I really needed to be on a daily medication instead of just taking ativan when it got really bad.
Avatar n tn Although plavix and aspirin are anti-platelet agents, plavix has a different mechanism of action that seems to be specialized for drug eluding stent to prevent restenosis. Laviquin is an antibiotic medication! and there is a class-action suit against Laviqiin providers that is currently unresolved.