if it is from coronary disease and/or coronary spasm, then medicines like
diltiazem as well as other classes of medicines (like beta blockers
and nitrates) can help alleviate the discomfort. In some patients, the disease becomes advanced enough to require angioplasty to alleviate the discomfort.
In terms of esophageal spasm, while not life threatening, this can be quite uncomfortable and is often mistaken for coronary angina.