The review, published online in The Lancet on June 7, includes all papers
1985 and 2006 on the safety, efficacy, and side effects of
statins. Armitage notes that since statins were first approved in 1987,
their ability to reduce the risks of vascular death, non-fatal MI, stroke,
and the need for arterial revascularization has been shown by several large,
high-quality randomized trials.