The first review shows the importance of chronic inflammation in AD, followed by three articles presenting evidence on the involvement of spirochetes, Chlamydia pneumoniae and Herpes simplex virus type 1
in AD. These are followed by a
review of amyloid proteins, which occur
in many cellular forms
in Eukaryotes and Prokaryotes.
"The link between several viral and bacterial infections and the most significant genetic factor for AD, APOE å4, is discussed in the next review.