As opposed to European (EASL) 2012, Asian-Pacific (APASL) 2012, American (AASLD) 2009, and World Health Organisation (WHO) 2015 major
guidelines for the treatment of chronic Hepatitis B, the following 3 guidelines are more strict on the conditions leading to necessity of treatment for Hepatitis B, HBeAg negative carriers:
Canadian 2009, Japanese (JSH) 2013, and UK/British (NICE) 2013 guidelines are more "strict" when it comes to treatment of negative HBsAg patients, especially in the