His sister has almost bled out (fatally) twice. I test positive
for it. And my niece could be the poster child
for the disease, having all the classic symptoms: post-op hemorrhage for a tonsillectomy age 12, seriously severe menstual periods, ongoing iron-deficiency anemia, easy bruising - you get the picture.
VWD can be hard to prove with the blood tests because many things make the Von Willebrands Factor (the protein that is deficient) go up and down, so false negative tests are common.