I have been on Cymbalta (60 mg) for over two years for treatment of fibromyalgia/depression/anxiety. I recently went down to 40 mg, and after two days was a basket case. Constant brain zaps
, a feeling like my entire brain was bruised, severe body aches, increased anxiety and agitation/aggression (which to me was the most frightening). I went back up to 60 mg. Four days later, I am still experiencing the bruised brain feeling and anxiety.