Nothing, surgery, stent(s), angioplasty, chemicals, dietary change, reduce arterial inflammation, or some combination
of these actions. Most patients will do whatever their cardiologist recommends, as I did.
Some day someone (not the major drug companies, who love things the way they are) will develop a process whereby plaque can safely be removed from arteries, and this issue will become moot. But most of us will be long gone by then.