Crestor muscle damage

Common Questions and Answers about Crestor muscle damage

crestor

The agency singled out atorvastatin (Lipitor), rosuvastatin (Crestor), and simvastatin (Zocor) for the new warnings and restated a warning about mixing lovastatin (Mevacor) with HIV and HCV drugs. Today's FDA safety communication follows label changes announced Tuesday that added cautions about new onset diabetes and transient memory problems for users of any of the cholesterol-lowering drugs in the statin class.
I have muscle spasm in or around the ribs on both sides (in the front under the breast and sometimes in the back at the same horizontal position), it feels like a ball rolling, in that it switches sides. It occurs even at night during sleep, painful enough to wake me. I only know that when I relax and stretch (the side where the knot is) using several positions I have to wait till it goes away, in many cases to have it return in other places described above.
http://www.medhelp.org/drugs/Crestor/show/3468 Lipitor: http://www.medhelp.org/drugs/Lipitor/show/3078 Thousands of articles on the research: http://news.google.com/news?
Apparently, though, there may not be any REAL damage to the muscles in most cases, in spite of the intensity of the pain. There are blood tests to determine if actual muscle damage is occurring. Here is an article about that: http://blogs.webmd.com/cholesterol-management/2008/02/statins-and-muscle-pain.html In any case, this is probably not a medical emergency that requires going the ER.
For some reason, I keep coming back to something in the muscle. Maybe a lactic acid build up or something similar. My daughter is 31 and has always been on the go. Constantly on her feet, working etc. This has brought her to a stop to where she can hardly function. Her problem started a little over a year ago while we were on vacation in Las Vegas. If you have heard from anyone else, please, please contact me at ***@****.
THere is an inc'd risk of muscle damage due to crestor type meds in patients with untreated hypothyroidism.
I was on Lipitor, then on Pravachol and lastly on Crestor. None of them had problems loweting the Choesterol levels, but muscle and joint pain even with Vit D and Co Q10 as prescribed my physician. However, I came off crestor yesterday as I started feeling Dizzy. I am normally a "healthy", active energetic person. Now my doc thinks we should try Zetia which is in a different family of drugs. Has anyone experienced difficulties with this? Any thoughts?
Due to the stent, there should be adequate blood flow to the heart muscle and if no permanent heart damage has occurred, it should all return to normal again. It sounds as though his heart attack was severe, and he was lucky that Doctors managed to bring him back. Does he have any known permanent heart tissue damage? Anti cholesterol medication is one measure, but isn't he on aspirin also? this is vital to lower the risk of another severe heart attack.
Lori, all the cholesterol meds work in slightly different fashions, so you may want to consider talking to your doc about trying a different brand like Crestor, or? You could also discuss the use of red yeast rice, if your doc is a functional medicine doc, or perhaps think about trying the niacin-based meds. Cholesterol meds can cause muscle weakness and pain. No matter what you're on in the future, make sure the doc checks your enzyme levels regularly.
My next step is to request a test that can determine where the muscle damage is. (Recently found out this is possible).
He didn't even run labs (poor guy was fasting and famished). He pulled him off the Crestor -- too many muscle issues - too much risk.
Muscle/tendon pains may relate to Crestor as it does in my case as well as several neighbors
I recently received an above avaerage ggt result (127)..I am healthy very athletic 58 year old male ... 5'7" 180 lbs..run 20 -30 miles aweek, weight training 3x per week, very strict diet, no red meat in 12 years & no alcohol..i do have high cholesterol & having been taking crestor for 3 years...i also have chronic back pain & recently tore my a muscle in my calf for which i was taking percocet prn..
I have been on Lipitor for over 20 years, only 10mg, but I quit taking them a month ago, I have sever nerve damage and muscle atrophy, but it is a toss up if it was caused by Post Polio Syndrome or Statins? Dr. OZ had a Cardiologist as guest on his show and stated that only people with severe blockage issues should take Statins. Would have been nice if they would have said this 30 years ago when the whole medical profession was pushing Statins like Heroin Dealers.
Because of the advice I received on here, I and my husband stopped taking ours, and our muscle pain has disappeared. My husband could barely walk due to leg pain, could not exercise due to muscle weakness, and now this is gone. So, I did my own research and was shocked to learn about statins and all the problems they cause. Our doctors have approved of us stopping these, so we did the right thing.
Some statins cause abdominal pains in some people, or nausea or serious muscle cramps and even damage. So I don't think it's just picking the one which you feel has the best affects, it's which one suits your body the best. In most cases I've read about, statins have hardly affected HDL levels, in fact most people have trouble raising them. When statins lower LDL, this automatically makes the HDL a higher proportion than it was.
Blood test (I believe CK and other relevant test to check heart muscle damage) It was ok and then got discharged. However during the stay at hospital here I saw on the heart monitor when I get irregular beat it showed as PVC. This is continuously there. I informed my Cardiologist which he requested to perform exercise ECG and radioactive tracer to check the heart. That result too had no issue. My problem is I still have chest pains, left arm pain and PVC's during the day.
Fat-soluble statins like Lipitor and Zocor cause more damage than water soluble statins like Pravachol and Crestor. Hence the latter should be tried at lower dose. Possibility of hypothyroidism and diabetes should be ruled out as the presence of either disease can complicate the muscle pain. The role of Co Q10 in lowering cholesterol is controversial and should not be tried without consulting your doctor. Please discuss these points with your treating physician.
I was on the statin Crestor in 2005 and at that time lost 42 or more pounds and developed severe mass muscle damage and a skeletal look., nausea, and fatigue. I have not been well for 4 or so years and I cant seem to be able to get over 105 lbs..I am 5'4' slight build, but was ever so skeletal and still not looking all that good..
Myopathy manifested as muscle pain and/or weakness associated with grossly elevated creatine kinase exceeding ten times the upper limit of normal has been reported occasionally. Rhabdomyolysis has also occurred rarely, which may be accompanied by acute renal failure secondary to myoglobinuria and may result in death. MANAGEMENT: Due to the potential for severe interaction, concomitant use of atorvastatin, lovastatin, or simvastatin with telaprevir is considered contraindicated.
About 2 years ago, in 2009, my LDL become slightly elevated, around 140-150, and stayed that way. Last month I started with Crestor, 5 mg, and in just 5 weeks, LDL dropped to 81, and total cholest dropped to 154 (from above 200 since 2009) My question is this: Is there a connection between HDL and liver? Can HDL be elevated to normal levels? If yes, how? How important is this (HDL) ?
This is odcourse just a guess and it could be a nuber of things causing this but from what you describe it sounds reasonable to guess nerve damage. I have the same problem and mine was attributed to my back and nerve damage. Of course some others will come along soon and share their opinions and you can go from there but I would suggest you see your Dr to have the test run that you ned to find the problem.
) I have high cholesterol (240) currently on crestor, difficulty losing weight (unless I eat practically nothing), forgetfulness...etc. I took levothyroxin for years but really never saw any significant changes in those symptoms. I never did any research just figured that was the way it is was going to always be. We moved a year ago to a much colder climate (hence the self diagnosis of raynauds) and took my sweet time finding a new doctor.
There are many causes of CPK elevation and muscle damage. Certain medications, trauma, inflammation (myositis), alcohol, genetic problems with the muscle, and viral infections can all cause CPK elevation. CPK is an enzyme that is found within muscle cells. When the muscle cells are damaged for any reason, the CPK is released into the blood resulting to increased levels in the test. I would recommend that you continue monitoring your CPK levels and have regular follow-up with your doctor.
What the Doctor is saying in the reply is that the cardiac output can show if any muscle damage has occurred, in other words, how well your heart muscle is working. This is usually stated as an EF percentage, for example EF 60 % or LVEF 60%. Maybe it is on your reports somewhere? If it is there, and it says 60 %, don't panic, because no ones heart reads as 100%. Normal is somewhere between 55 and 75. I hope this helps.
You should be getting annual blood tests to check your liver functions and watching for signs of muscle damage. Having said that, statins are very safe and side effects are quite rare. I would be interested to know why your doctor wants you off the meds as well. Has he seen something in a blood test or trying to save you money? Let us know.
there are trials already i posted in the past, also the effect of sim on liver was reviwed by liver researchers and they said it has no toxicity the elevations of alt that can happen on few are due to a balance of lipids not toxicity because the alt elevation is transient and resolve itself the only serious side effect of sim that can happen is muscle damage or mitocondrial discorder, very rare statins cause acute liver failure in chronic hbv patients?
Some side effects of Crestor are: unexplained muscle pain, tenderness, or weakness; fever, unusual tiredness, and dark colored urine; swelling, weight gain, urinating less than usual or not at all; or nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
One regular strength tablet of acetaminophen may cause damage to a cat’s red blood cells, limiting their ability to carry oxygen. In dogs, acetaminophen leads to liver failure and, in large doses, red blood cell damage. 3) Antidepressants (e.g. Effexor, Cymbalta, Prozac, Lexapro) While these antidepressant drugs are occasionally used in pets, overdoses can lead to serious neurological problems such as sedation, incoordination, tremors and seizures.
Recently I began experiencing debilitating muscle cramps and spasms in my upper thighs. I can literally feel the muscles rolling and tightening under my skin. Nothing helps them. They occur mostly at night, but bending my leg too much can also trigger an attack. My pharmacist says its from the Lipitor. My doctor says its from Vitamin D and Magnesium deficiencies.
MedHelp Health Answers