Crestor and muscle damage
Common Questions and Answers about Crestor and muscle damage
crestor
After 7 years of therapy taking Crestor and Tricor (fenofibrate), I, too, started experiencing intense pain in my legs, feet, back, and arms. My Dr. took me off Crestor last month but the pain returned within a few days, although not as intense as it was prior to my stopping Crestor. I took myself off fenofibrate just a couple of days ago and "Wow" what a difference! I can actually sleep at night and notice that the pain is dissipating more and more each day.
Fat-soluble statins like Lipitor and Zocor cause more damage than water soluble statins like Pravachol and Crestor. Hence the latter should be tried at lower dose. Possibility of hypothyroidism and diabetes should be ruled out as the presence of either disease can complicate the muscle pain. Please discuss these points with your treating physician. It is difficult to comment beyond this at this stage.
Hope this helps. Please let me know if there is any thing else and do keep me posted.
Remember that these drugs [statins] are often associated with side-effects including nausea, headaches, dizziness, sleep disturbances, sexual dysfunction, fatigue, shortness of breath, memory loss, liver problems, muscle weakness, muscle pain, peripheral neuropathy and cardiomyopathy due to a depletion of Coenzyme Q10.
Statins create a whole set of side effects of their own and studies are showing that while they reduce cholesterol levels, their use does not prevent heart attacks. I had a doctor who insisted that I go on Crestor when I was hypo and my cholesterol was high and I refused. My cholesterol has since come back within normal limits without the use of statins.
Due to the stent, there should be adequate blood flow to the heart muscle and if no permanent heart damage has occurred, it should all return to normal again. It sounds as though his heart attack was severe, and he was lucky that Doctors managed to bring him back. Does he have any known permanent heart tissue damage?
Anti cholesterol medication is one measure, but isn't he on aspirin also? this is vital to lower the risk of another severe heart attack.
But my best lipid results ( raising HDL, lowering LDL and Lp(a) ) came from taking RX Niacin which I take with the 10 mg Crestor and 325 mg aspirin at bedtime.No problems with Niacin either.I take RX fish oil also as I am in big time prevention mode due to cardiac microvascular dysfunction.Fortunately my lipids have never been bad and my larger coronaries are clear but the lipids are only a piece of the total cardiac picture and the possible side effects of meds far outweigh my other risks.
In January (when this latest blood work came in) it showed that my cholesterol was a bit elevated, so my doctor put me on Crestor. I took for only two months and started having severe muscle pain in my legs and arms. I stopped taking it immediately. I might also add that I was diagnosed with Gastroparesis about three years ago. I was also diagnosed with IBS-Constipation prevalent roughly four years ago.
1) In studies comparing equal doses of Crestor to Lipitor, Crestor has been shown to lower LDL levels ~10% and increase HDL levels 2-4% more than Lipitor. Your triglyerides, total cholesterol, and LDL's are in the optimal range, and your HDL level is in the middle. Based on these numbers, there doesn't seem to be a need to switch to Crestor.
2) There is little evidence on the use of EPA alone.
my doc took me off simvastatin and changed me to the lowest dose of crestor 5 mg.
Had been on Augmentin for a sinus infection, just finishing up the script, and take Crestor, Nexium, and Zyrtec on a regular basis. Symptoms started a few days after starting generic Zyrtec, which also caused unbelievable dryness that felt like I was dehydrated (no vomiting, though). A day after the chills, I noticed my urine was dark and my stools were very light, almost gray, and I started getting very itchy but no rash.
I would need to know what side effects and how long you were on the drugs. Typically, the normal muscle pains will be gone in a day or two. The more severe side effects can last longer. Are you sure the side effects were from the statin as the listed side effects are very common to many conditions. In studies, just as many on the placebo control group reported side effects as the statin control group, about 1 in 2,221.
Let us know.
Are you sure your muscle pain is related to the statin use? Muscle pains are the most common complaint and has many, many causes. In any case, there is no danger in stopping Crestor suddenly, but discuss it with your doctor.
I would have a couple questions for your doctor. First off, why does he have a target of an LDL under 100? That is normally the recommendation for people at high risk of heart disease or those that already have heart disease.
Lori, all the cholesterol meds work in slightly different fashions, so you may want to consider talking to your doc about trying a different brand like Crestor, or? You could also discuss the use of red yeast rice, if your doc is a functional medicine doc, or perhaps think about trying the niacin-based meds.
Cholesterol meds can cause muscle weakness and pain. No matter what you're on in the future, make sure the doc checks your enzyme levels regularly.
However, there is also the risk of liver inflammation due to the medicine Crestor® (rosuvastatin) and it is conceivable that there could be an additive effect of Crestor® (rosuvastatin) and INH. In addition, niacin may increase the risk of muscle disease called myopathy when used with Crestor® (rosuvastatin). Crestor® (rosuvastatin) significantly increases the INR (enhances the effect of Coumadin to make your blood “thinner” than it would be alone.
put on another drug which is not a statin. One year has passed and he still has high CK levels and very severe and weak legs. He tries to exercise but can't do it for long. Calf muscles jump all the time and are tender. He can't walk around the block. He gets cramps in his legs at night as well.
What can we do to help this condition? Are there drugs or natural supplements to help build up the damage muscles?
What exactly do you think my husband's condition is?
Because of the advice I received on here, I and my husband stopped taking ours, and our muscle pain has disappeared. My husband could barely walk due to leg pain, could not exercise due to muscle weakness, and now this is gone. So, I did my own research and was shocked to learn about statins and all the problems they cause. Our doctors have approved of us stopping these, so we did the right thing.
I faxed him the results to this lab work and he wanted to recheck it in 4 weeks as he felt it might be viral. I am on Crestor, Linsoprosil, Omneprozole and Testosterone Inj for low testosterone syndrome. I have been under stress from quitting chewing and was not feeling well about a week before this blood test and gave myself a testosterone injection about 3-5 days before blood work.
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