Crestor and liver enzymes

Common Questions and Answers about Crestor and liver enzymes

crestor

Today I started on 2.5 mg of Crestor. I had been off statins for some time because of ^ liver enzymes. I was taking Zetia and using Promise Active margerine, etc.
It is possible that the Crestor is responsible for the elevated liver enzymes. I agree with the ultrasound and the blood tests for hepatitis. If the liver enzymes continue to rise, a liver biopsy should be considered. I would also discuss stopping the Crestor in light of the elevated liver enzymes. Abstaining from alcohol should also be considered. These options can be discussed with your personal physician. Followup with your personal physician is essential.
There are a lot of things that can elevate liver enzymes and you need to find out if it's the supplement or something else.
All - I got my bloodwork back. Liver enzymes normal and no hepatitis. Doc thinks it was just a cold or a virus. Thanks for all comments.
Liver Enzyme Abnormalities and Monitoring It is recommended that liver enzyme tests be performed before and at 12 weeks following both the initiation of therapy and any elevation of dose, and periodically (e.g., semiannually) thereafter. Increases in serum transaminases [AST (SGOT) or ALT (SGPT)] have been reported with HMG-CoA reductase inhibitors, including CRESTOR.
-- Long-term use of cholesterol-lowering statins does not increase the risk of liver disease in patients with abnormal liver function, and can actually improve liver function, according to a new study that challenges widespread belief. The researchers also pointed out that this study is the first to show that statins provide a substantially greater cardiovascular benefit in patients with abnormal liver function than in those with normal liver function. The study, published in the Nov.
I recently had blood test done and my liver enzymes were both 338 and 336 which are extremely high. My other tests results were all normal. I have been on .5mg of crestor for 2 years and have had not inflated levels. I had a tooth pulled and was on locet 10mg (and davecet) for 5 days and then took the blood tests. Could my being on the lorecet and davecet have caused this inflated liver enzyme level? I have been working out at a gym and swimming for 4 months now.
He told me to stop taking the zyrtec and ordered liver function tests. Well, tests came back with high enzymes and bilirubin and he told me to stop taking ALL medications. Ordered an ultrasound which he said was negative, and ordered the blood work again. He seems to think it's liver damage due to drug toxicity. Problem is, he doesn't seem to be able to tell me what I should be doing, other than not taking my meds, to get healthy again.
my sister-in-law had elevated liver enzymes and couldn't think of any meds she was on that would raise her numbers. She decided to lower her consumption of diet cola thinking the aspertame might be causing probs and her numbers did go down. When my liver numbers tested higher, I also cut the aspertame and my numbers went down. Is it a coincidence or not, I don't know.
Statins can, in some patients, induce elevated liver enzymes. This could be the reason. This is something you should discuss with your doctor because there are differences of opinion as to the correct approach when statins appear to elevate enzymes. I also think your doctor owes you a more complete explanation as to what in your labs suggests that you should discontinue Crestor.
90, to 1.27 which gave me a high rating. Would crestor be the cause, and Is that high enough to be concerned about changing the meds?
My (total) cholesterol levels have gone from 262 in 06/04 (prior to starting Crestor) to 155 in 11/05 so the low dose Crestor (and I believe the red wine helps) seems to be getting great results. My HDL stays in the mid 30's and my triglycerides have gone from 321 down to 162, for the same time period. Finally, I have scheduled an appt. with my Family Physician for early December. What further tests should I seek? Also, please tell me any other impressions or concerns whatsoever.
) A doctor wanted to put me on statins about 3 years ago. I said no, my liver enzymes had been elevated in the past and I did not want to go on them. Plus I hate taking pills. I said let me try to lower it by diet first. He sad, "Okay, but diet change won't work." Frankly, I am not sure where he got that idea. He was young, so maybe the was too young to remember when people did modify their diets and drop their cholesterol.
Can't get straight answer from my cardiologist either! I also need to lower my cholesterol and he wants me back on Lipitor. BUT, my liver enzymes go up and high. maddi_me states "less of two evils". Would also love to hear from someone. Hate this catch22.
I feel that he should watch what he suggests as the liver enzymes are just abit high and have not gone to a liver specialist since was diagnosed in 1995 with hep C. It was not active in 1995 but only have noticed a few flare ups since 1995 I dont think that is the problem here!.
If the increase is severe, you may need to stop taking it, which usually reverses the problem. If left unchecked, increased liver enzymes can lead to permanent liver damage. Certain other cholesterol-lowering drugs, such as gemfibrozil (Lopid) and niacin, increase the risk of liver problems even more in people who take statins. Because liver problems may develop without symptoms, people who take statins have their liver function tested periodically....." See: http://www.mayoclinic.
I went off Crestor about 6 months ago and since then my triglycerides have doubled to 186. In the last month my ALT/AST liver enyzmes have started to elevate. I was wondering is it possible that discontinuing crestor allowed my triglycerides to elevate which may of let my Fatty liver get worse? We hear about people coming off of Crestor because of liver damage but is it possible that coming off a statin can make fatty liver worse and then enyzmes show up elevated? Thanks in advance.
and recently Topomax 25 mg bid. Here of late my liver enzymes have been slightly elevated. My crestor was d/c'd. My internist wants me to go to AA. I am a functioning nurse that does not want to abstain totally. The enzymes were not high. What do you think. I know in a perfect world I should just quit drinking, but I am not perfect. In all probability, what is the elevation due to, Crestor or alcohol? I drink about 4-5 beers a night. Thank You.
I had my Gallbaldder removed in March 0f 2012 and a Ultra Sound of the liver done in the later part of 2012, the results were normal and my enzymes were ok at that time. I am going to see a Gi Dr. in April.
Cholostrol results were pretty much under control as I am on medication (Crestor). Since my liver enzymes were high, I went thru the ultrasound whose findings were as follows: 1. Mild diffuse fatty liver infiltration 2. Findings Suspicious for focal adenomyomatosis involving gallbladder body anteriorly 3. Slight increased echogencity and hetrogeneous echotexture of the liver, compatible with mild fatty infiltration 4. The Liver measures 14 cms without discrete lesion. 5.
elevated liver enzymes by patriciabarry, Oct 18, 2009 02:51PM My 59 year old husband had radical surgery for small cell bladder cancer just three weeks ago. He had neoadjuvant chemo with etoposide and carboplatin ending eight weeks ago. He takes allopurinol for gout, plavix because of a previous stroke and crestor for high cholesteral. He also recently took indocin for a gout attack. The pathology came back negative for invasion in the lymph nodes and the prostate and the left kidney.
He takes allopurinol for gout, plavix because of a previous stroke and crestor for high cholesteral. He also recently took indocin for a gout attack. The pathology came back negative for invasion in the lymph nodes and the prostate and the left kidney. My guestion has to do with his most recent blood test. His AST 145, LDH 202, alt 229, ALK Phophatase 259 Bilirubin .8. The Oncologist is concerned that the cancer may have gone into his liver and/or bones.
Unfortunately, in some, taking cholesterol lowering meds can elevate the liver enzymes. I believe your doc may have asked you to discontinue the lipitor to see if that is the cause of the elevation.
my liver tests are high I have a test every month without fail. In the past 6 months I have two that has come back normal the rest has not. Ask your doc if your chorlestrol drug is doing it.. They dont know why mine is high. I dont drink. You could try a very low fat deit and see if that brings your count down. I treid that but it did not work for me . Let us know how you get on.
Phros 205. I take Crestor 20mg and Lininopril 30mg. Had a ultra sound of the liver in the later part of 2012...it was normal and at that time my liver enzymes were good. I also had my Gallbladder removed in March of 2012. .
I was put on Lipitior and it raised my liver enzymes. Now I am on Crestor and it works great and cholesterol is normal.
I was in a blinded research study for cholesterol and finished the drug about 4 months ago. I had a baseline MRI which was normal and mid way through had high level liver enzymes and then my 2nd MRI showed abnormalities. This led me to the conclusion that yes I was on the actual medicine and not the placebo. I was also taking my normal routine medication which consisted of 40 mg Crestor, Zetia and 145mg Tricor along w/ Fish oil and Niacin.
Are you on drugs for your cholesterol and HDL etc. yet? if so they and some other drugs can cause liver enzyme elevation. Think about the drugs whether prescription or not that you have had and see if their side effects effect the liver. If not then I would think about getting on Crestor (a statin drug to lower your cholesterol and LDL and raise the HDL.
But, you probably need to get on a statin drug such as Crestor. Your liver enzymes will have to be monitored though as these can be affected by statin drugs.
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