Crestor and cpk
Common Questions and Answers about Crestor and cpk
crestor
I am diabetic since 6 years, two years back i discovered that my Lipo is high( cholestrol 290, LDL and HDL),i start taking Crestor and after that i discovered that my CPK level is 600. i stoped it for two months and went down to 450 , due being Hypolipid i couldn't control cholestrol by exercise or food so i changed three doctors and each gave me a different Statins and the CPK now reaches 1375 . , i tried Ezytrol for a while but it's effect was very low .
Because of aches and pains, my primary care physician ordered a panel of blood tests and all was normal except for the CPK which was 117. He gave me an antibiotic and after a week, checked the CPK again and found it to be 139. He wants me to see a rheumatologist but an available appointment will be months away. I am 75 and have been on Vytorin for at least 5 years as well as Actonel. My bone scan last year was good for someone my age. What should I do while waiting to see an arthritis doctor?
My father needs to lower his cholesterol, but Statins cause him significant muscle problems (Myositis) and elevated Creatine Kinase CPK and Aldalase. His symptoms resolve and tests return to normal when the Statins are discontinued.
What Cholesterol drugs can he try that do not have Myositis as a side effect?
Fat-soluble statins like Lipitor and Zocor cause more damage than water soluble statins like Pravachol and Crestor. Hence the latter should be tried at lower dose. Possibility of hypothyroidism and diabetes should be ruled out as the presence of either disease can complicate the muscle pain. Please discuss these points with your treating physician. It is difficult to comment beyond this at this stage.
Hope this helps. Please let me know if there is any thing else and do keep me posted.
Certain medications, trauma, inflammation (myositis), alcohol, genetic problems with the muscle, and viral infections can all cause CPK elevation. CPK is an enzyme that is found within muscle cells. When the muscle cells are damaged for any reason, the CPK is released into the blood resulting to increased levels in the test. I would recommend that you continue monitoring your CPK levels and have regular follow-up with your doctor. Take care and regards.
I am a 72 year old active women who has been diagnosed with osteo arthritis who has been sent to my cardiologist because of the my consistant high cpk reading. After electrograms, changes in cholestrol medication,( lipitor, crestor,), now on zetia my tests keep coming in high.Outside of my lower extremities aches, which I credit to arthritis, I feel fine. Both doctors, arthritis and cardiologist, keep drawing blood with these rates still climbing.
Even though there is no blood test for fibromyalgia, blood tests are important to exclude other medical conditions. Therefore, thyroid hormone and calcium blood levels are obtained to exclude hypercalcemia, hyperparathyroidism, and hypothyroidism. The blood alkaline phosphatase (a bone enzyme) level is often raised in patients with Paget's disease of the bone. The CPK (a muscle enzyme) level is often elevated in patients with polymyositis, a disease with diffuse muscle inflammation.
After 7 years of therapy taking Crestor and Tricor (fenofibrate), I, too, started experiencing intense pain in my legs, feet, back, and arms. My Dr. took me off Crestor last month but the pain returned within a few days, although not as intense as it was prior to my stopping Crestor. I took myself off fenofibrate just a couple of days ago and "Wow" what a difference! I can actually sleep at night and notice that the pain is dissipating more and more each day.
I started on crestor, than realized I am ttc and starting not feeling well and am on my ttw...I test for my pregnancy saturday. I took the crestor for 4 days than stopped and its been a little over a week. Should I restart and then stop if pregnant or not bother because of the possibility of there being a fetus?
I am just worried about my health.
The weakness and aching are signs of rhabdomyalgia which is a side affect of statin drugs. You need to see the doctor that prescribed the meds as he/she needs to check you. I don't know about the shortness of breath. It could be a drug reaction too.
I have connected the neurologist and my carteologist (2007 bypass) and the next step they are taking is to do the normal CPK blood test. It is time for that anyway and will rule out the statin. It is the only medication I am taking other than asprin. All other tests are coming in negative. Spinal tap is likely to follow shortly.
Side note. I am 55 and have not experienced double vision before, nor am I awar of any family history.
Apprecaite your thoughts.
CPK is found in skeletal muscle and myocardium (heart muscle). Lipitor can cause various levels of elevation and associated symptoms like muscle aches, weakness and atrophy. The elevated CPK may be of no consequence or it may cause serious problems depending upon the degree of elevation and the symptoms. A severely elevated CPK can cause liver damage. I would consult with your physician to determine if this is a new finding.
Has anyone gotten worsening of their PVC's from taking a statin drug? I seem to be intolerant of these drugs and have tried Crestor, Lipitor and Lescol. My PVC's go absolutely nuts when I take them. I have done my own tests by going off and on them. I consistently get worse when I'm on them. I take C0Q10 and a whole bunch of supplements including magnesium to no avail. Any feedback would be appreciated.
CPK-1 or CPK-BB is elevated in brain or lung pathology. CPK-MB or CPK-2 in heart pathology and CPK-3 or CPK-MM is elevated if skeletal muscles are the cause.
I think you should discuss these possibilities with your doctor. It is difficult to comment beyond this without examining. A comprehensive investigation is required keeping all the points in mind. Take care!
Fat-soluble statins like Lipitor and Zocor cause more damage than water soluble statins like Pravachol and Crestor. Hence the latter should be tried at lower dose. Possibility of hypothyroidism and diabetes should be ruled out as the presence of either disease can complicate the muscle pain. The role of Co Q10 in lowering cholesterol is controversial and should not be tried without consulting your doctor. Please discuss these points with your treating physician.
Other symptoms are anxiety, cough, dizziness, palpitations, shortness of breath etc. your doctor would like to check the cardiac enzymes like troponin and CPK, CPK MB. Continuous oxygen and morphine, anti thrombolytic therapy, anti arrhythmic, etc are required. You need to get an MRI cervical spine to check for any prolapsed disc or degeneration. Hope this helps. Take care.
I have gone off them from time to time and, after my CPK levels dropped, gone back on them. Recently I went off the statins because my CPK level was around 430. After being off of the statins for about two months, my CPK level actually went up to 640. I was tested again last week (after another two weeks) and my CPK was 730. My doctor just ordered an Aldolase test to see if that was normal.
I have frequent cramping and muscle tightness in my legs.
CPK-1 found mostly in the brain and lungs and higher than normal level is associated with the pathology of brain and lungs. Similarly, higher CPK-2 level is associated with heart pathology. Additionally, CPK-3 is associated with muscle inflammation or injury. Therefore, i would recommend you consult with your doctor for a better insight of the situation to know which CPK is elevated in your case. Hope this helps.
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