I too noticed it says to take with food, which I did until I had been on it for a month - then I tried taking it a few times without food. I had no change in any
side effects (dizziness. etc), so for me, it doesn't seem to matter -but then again, it's only one of 3 BPmeds I'm currently taking to control my BP, so that may be a factor as well.
Generally speaking, taking a med with food means a slower absorption rate of the med, which can help ease some side effects.