One of the BP meds I take daily is
generic Coreg 25mgs, twice daily. I too noticed it says to take with food, which I did until I had been on it for a month - then I tried taking it a few times without food. I had no change in any side effects (dizziness. etc), so for me, it doesn't seem to matter -but then again, it's only one of 3 BPmeds I'm currently taking to control my BP, so that may be a factor as well.