Do the welts itch
? I started on Copaxone
, but 4 and 1/2 weeks into it, we learned that I was allergic to it. The welts weren't going away, and with each new injection, all of the welts would itch.
My MS Specialist put me on Rebif, and I haven't had any site reactions, at all.
One thing my Rebif nurse told me, was to massage the injection site with a warm damp cloth, in a circular motion for two minutes, to disperse the medication.
Maybe that would help your wife.