Combining these medications may significantly increase the blood levels
and effects
of silodosin. This may cause blood pressure to fall excessively
and heart rate to increase, especially when you rise from a sitting or lying position. The risk of other side effects such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity) may also increase.