Clopidogrel and bleeding

Common Questions and Answers about Clopidogrel and bleeding

plavix

My consultant recently prescribed me Plavix/Clopidogrel to take with Aspirin following possible TIAs. I have been taking 75mg Aspirin, 75mg Plavix/clopidogrel and 15mg lansoprazole daily for just over a week. Yesturday every time I bent down (quite a lot as I have a baby) or stood up too quick I have been suffering a dizzy feeling and it sometimes takes me a while to get my head together.
I had a double bowel obstruction requiring emergency surgery immediately several years ago when taking plavix, and bleeding was a concern and a problem during the surgery. That being said, I'm still standing.
But as of now, I saw just below the wrist a blue/green bruise and some reddish round spots. I was advised by the cardiologist to stop the “Pevodex-clopidogreland continue the rest inclusive Aspirin !!. Is is advisable to discontinue “PEVODEX” immediately or could you dr.,please give me a kind advice of my situation.I would send you the ECG print by attachment if required. Appreciate and look forward to your much concern and a good advice as soon as possible. I apologise to write so much .
It seems plavix helps reduce the risk for clots at implant site, and after a year the risk of clots is less than the risk of excessive bleeding with plavix. After a year discontinued plavix and remain on a baby aspirin. Several months ago after some dental work there was excessive bleeding for hours on a baby aspirin...so I'm not cool with large doses of anti-platelet meds. Warfarin can cause very serious (possibly fatal) bleeding.
I received a copy of a letter today, sent from my Cardiologist to my general Doctor, and it states that my coronary artery stenting last week gave excellent results. What concerns me is the statement at the bottom "I suggest taking aspiring and clopidogrel for a period of one year". Surely not? Aspirin too? Is he nuts?
Plavix is clopidogrel which is an inhibitor of platelet aggregation.Thus it interferes with clotting and can lead to increase in bleeding even with a minor cut.
Same as Ed, I've eight stents and always was given a handful of Clopidogrel (Plavix) during the prep time before the surgery, and a couple of aspirins. They want the blood as thin as possible during the procedure to reduce the risk of stroke or arterial obstructions, obviously. I'd not be concerned and take the medication as asked. Best wishes with the procedure, keep us informed.
I have been on Coumadin for 18 years due to Lupus Anticoagulant (Antiphospholipid Syndrome) and several DVTs. In 2005 had MI with occlusion of the LAD artery and had drug stent inserted and I am still on plavix. My doc has debated when to take me off the Plavix safely....what are the recent studies about this dilemma? thanks so much!
The recommended treatment for DES implants is dual therapy of aspirin and plavix up to a year. Combining plavix and aspirin increases the risk of bleeding vs. aspirin alone in patients treated for more than a brief period of time. That is the regimen followed for my DES implant. f you are in this category a prior MI and unstable angina:" In the CAPRIE trial, clopidogrel (plavix) was equivalent to aspirin for patients with a recent (but not acute) MI.
ClopivasAP150 is a combination of anti-platelet drug clopidogrel and blood thinner aspirin. If there is an internal bleed, and this drug is continued, then it can worsen the bleed. Depending on the location of the bleed, an increased bleed can become life threatening. Please consult your doctor regarding this. Take care! The medical advice given should not be considered a substitute for medical care provided by a doctor who can examine you.
however, gastrointestinal bleeding may occur less often with clopidogrel. Clopidogrel is used to reduce stroke, myocardial infarction, and vascular death in patients with a history of recent stroke, recent myocardial infarction (MI), or established peripheral vascular disease. The CAPRIE study shows that it is more effective than aspirin in reducing atherosclerotic events in high risk patients.
5 months ago she had a massive stroke which has left her paralysed on the left side. (This is her 3rd stroke) Due to medicine she was taking she developed bleeding ulcers and had to be given blood. She was also dehydrated. Since leaving the hospital 3 weeks ago (she is now in a nursing facility) her oxygen levels continue to drop to 78. Her machine was on 5 1/2 this week and once they got her back to 92 they put it back to 3. even with the oxygen on it continues to drop.
The prolonged use of clopidogrel (Plavix) greatly reduces the risk of late thrombosis in DES, but clopidogrel itself poses problems. Aside from the expense and the risk of bleeding posed by the long-term use of this drug, using clopidogrel (because of the pronounced bleeding tendency it causes) essentially precludes any invasive medical procedures whatsoever.
Hello Abdul284 It is hard to give you an accurate assessment of the situation but generally speaking all coronary artery stents require uninterrupted use of aspirin and clopidogrel (ticagrelor or prasugrel may be alternative medications utilized). The duration of this therapy varies depending on stent type.
I had a heart attack in 2006, and my ulcer was bleeding at the time. I was on Nexium, and had just been switched to Prilosec. When I had the heart attack I had a 100o/o blockage and a 98% blockage and had 2 stents. I still have 6 small blockages so I cannot go off Plavix. My dr. took me off prilosec and put me on Protonix until my ulcer healed, then I took Pepcid AC 20 mg. He has recently had to put me back on Nexium for severe acid reflux, but told me to take Plavix in the morn.
To date there have been no reports of an important interaction in humans between warfarin and clopidogrel. Nonetheless, because warfarin increases the risk of bleeding, blood tests to measure the degree to which the blood is anti-coagulated or thinned (prothrombin time; INR) may be ordered to assess the degree of blood-thinning when warfarin and clopidogrel are used together.
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With me the flying comment was verbal, the booklet was instructions should bleeding occur and the signs of stroke etc. If you google flying after stent, then lots of sites appear. Most say a 2 week restriction but i cannot find any which say there is no restriction. Here is something interesting.... Researchers at Yale University have proposed guidelines for patients with cardiovascular diseases who wish to travel by air.
since this anti blood clotting medicine could cause bleeding at any time I am in total terror and Can you pl confirm , If there was no surgery or stent placing is done please confirm that clopidogrel 75mg and asprin 75mg can be stopped after taking them for 6 months.
It can cause perforation, bleeding into the abdomen and swelling due to ulcers causes narrowing in the duodenum and gastric outlet obstruction. Upper GI endoscopy is the commonest investigation and detection of H.Pylori is made by urea breath test, measurement of antibody levels in blood and detection of urease activity in a biopsy specimen by rapid urease test. For peptic ulcers, try raising the head of your bed about four inches with blocks.
While the use of clopidogrel may be effective, previous comparisons of another platelet inhibitor (aspirin) versus warfarin have demonstrated clear superiority of warfarin over aspirin for the prevention of strokes in atrial fibrillation. Also, to say that clopidogrel does not have the side effect of bleeding is simply not correct. The incidence of bleeding with clopidogrel is almost certainly less than that of warfarin, but the risk is still present. Hope that helps.
It is important to note that each supplement is capable of having a serious effect on blood coagulation and could cause serious bleeding. Taken together, this risk would be even higher, especially for individuals who are on anticoagulants, scheduled for a surgical procedure or already bleeding for any reason, such as ulcers or colitis. Quercetin drug interactions: Use with caution in individuals with a history of bleeding, hemostatic disorders, or drug-related hemostatic problems.
Her doctor is worried to give her Coumadin because of constant monitoring and risk of bleeding. My mother can still walk and do her activities of daily living except cooking and cleaning the house. Her ability to read is affected. At some point, i am still thankful to God that He gave us the chance to know the real cause of my mother's recurrent attacks. I just pray that he would take my mother's atrial fibrillation away and never come back for good.
An INR of 1 is how long normal blood takes to clot. An INR of 2 means it take twice as long and so it goes on. Aspirin and Clopidogrel (plavix) I believe attack the clotting mechanisms in different ways. Personally I don't think they know the long term outcomes. I in no way say you should do the same, but two years ago I went against my Doctor and Cardiologist and came off anti coagulants.
This discussion topic is a slippery slope of thoughts, studies, and opinions. I have both bare-metal and drug eluding stents in place, four of each, and took Plavix for twelve years. I was asked to take the drug not only to keep clots from forming in my stents, but also to maximize blood flow in what are called collateral arteries, little ones that develop to help supply damaged areas of the heart.
stopped taking clopidogrel and were followed up for an additional 12 months. At 18-month follow-up, there was no difference between patients with a drug-eluting or bare-metal stent in cumulative rates of death or myocardial infarction (MI). However, after clopidogrel discontinuation patients receiving drug-eluting vs bare-metal stents experienced higher rates of death and MI (4.9% vs 1.3%, respectively).
There are no documented evidence that plavix causes stomach bloating. Plavix is a medication that helps prevent clot formation, and there is increased risk for excessive bleeding.
I no longer have to take clopidogrel and effient wasn't around for me to use. However, I do remember reading some articles on this medication. Although it has been approved for patient use, it does have one concern. If you are on this drug and have surgery such as a bypass, it tends to cause severe bleeding, which can be fatal. Clopidrogrel (plavix) has no such problem attached to it. On the plus side, it reduces other risks dramatically and outperforms clopidogrel hands down.
The selection of the antithrombotic agent is usually based on the absolute risk of stroke and bleeding and the relative risk and benefit for a given patient. Based on the level of risk, most patients are either started on aspirin or Warfarin (Coumadin). Clopidogrel (Plavix) is an anti-platelet agent and acts via a different mechanism than coumadin does (coagulation pathway).
I have had scans from the chin down to the stomach and all appears ok apart from scarring in the lung from pheumonia 26 years ago. My diet is pretty good and I cycle regularly and am quite active even though my weight has increased by a stone since stopping smoking. I have prescribed drugs including Bisoprolol, Aspirin, Clopidogrel, Candesartan Cilexetil, Felodipine plus I take Solpadol for back pains occasionally. My Gp has been very good and the respiritory consultant has no concerns.
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