Seven patients, of whom five were hepatitis C positive, developed renal function impairment long after transplantation, as well as de novo
nephrotic syndrome (n = 5), severe hypertension (n = 5), nephritic
syndrome (n = 1), and increased serum creatinine (n = 1). This type III cryoglobulinemia was associated with membranoproliferative glomerulonephritis and with thrombi within the glomeruli in one case.