Hi. I'm on tamoxifen so I can't take any meds which inhibit cyp2D6 enzymes. I've been on almost ALL SSRI ( Effexor, lexapro, celexa
, nortriptyline, fetzima, & viibryd) & my depression worsens with them (suicidal thoughts, etc). The only one that has helped is remeron but every time I've had to return to remeron I gain weight. I'm usually 110-112 and eat very well & workout almost everyday.