I have a close family memeber, (a nurse also) has taken
Celebrex daily for a number of years.
It is very effective for relieving her severe bi-lateral knee pain and she feels the benefits out weight the risks. She is 49.
Celebrex may cause an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. All nonsteroidal anti-inflammatory drugs (NSAIDs) may have a similar risk. This risk may increase with duration of use.