Some meds cause release of histamine. Most common example is narcotics.
We may have an <span style = 'background-color: #dae8f4'>allergy</span>
to a med. I had blotchy hives on hand
s <span style = 'background-color: #dae8f4'>and</span>
feet for years until I realized I was allergic to NSAIDs - Non-Steroidal Anti-Inflammatory Drugs like ibuprofen, celebrex
, Naproxen. It is IMPOSSIBLE to effectively scratch the palms and
soles - the skin is too thick.
Sensitive skin is irritated sometimes with abrasion from tight clothing.