carvedilol in portal hypertension

So you are already taking 10mg of propranolol for your portal hypertension caused by your portal vein thrombosis (PVT). Propranolol is the most commonly used drug for portal vein obstruction. Combined with endoscopic banding treatment they are the standard first line of treatment. Do you know why she don't just increase the dosage? Now she wants to add another beta blocker in addition to propranolol? Has your doc talked to you about anticoagulation therapy?

When there is increased pressure in the portal vein, it causes a backflow of blood and in places where the portal and systemic veins anastomosis is there they engorge or swell up. The sites where this happens is the lower end of esophagus, around the umbilicus and in the rectum. Thia back flow also causes the enlargement of spleen. So, an effect of portal hypertension are the varices and splenomegaly. Hope this helped and do keep us posted.

But if you have liver disease that leads to cirrhosis, the chance of developing portal hypertension is high. A symptom of portal hypertension is ascites (an accumulation of fluid in the abdomen). When there is "huge" distension that condition can cause a rupture and a serious event. You should see a doctor to rule out any serious liver disorder, and determine the underlying cause of your chest and abdomen distention.

how bad is portal hypertension,and how long does it take to become a very nasty problem

I have recently been prescribed Amlodipine-Benaz 5/10 MG capsules for treatment of hypertension. However, my resting pulse rate has consistently been in the 90's and increasing into the 100's at time, so I have been prescribed Carvedilol to help control the heart rate. My question is, doesn't Carvedilol control hypertension as well...Why should I be taking carvedilol in addition to amliodipine?

In compensated hepatitis C–related cirrhotic patients, the proposed model…could replace hepatic venous pressure gradient for predicting portal-hypertension-related clinical decompensation," senior author Davide Festi, MD, from the University of Bologna in Italy, told delegates here at the International Liver Congress 2013. Dr.

Thanks for the response! It's good to be somewhat armed with some info before going in I think I am leaning towards the portolpulmonary hypertension as I do have portal hypertension, plus the hepatopulmonary syndrome's fix is a lung transplant so I'll just stick with the liver transplant :o) Maybe my hepa or cardiologist will refer me to UCSF which probably deals with this more often and is my transplant center. Are you with UCSF Hector or CPMC or ???

with further time hopefully the portal hypertension will also lessen or resolve. Alcohol-related cirrhosis is well known to cause portal hypertension in the setting of well preserved liver function, in large part due to the location of the scarring in the liver. remember also that even the liver numbers have improved you are still at risk for developing HCC, so you should have the appropriate surveillance.

Of course if someone has cirrhosis so advanced to have portal hypertension the abnormal architecture of the liver itself would be seen including changes in size of lobes and most especially the typical nodular liver itself. Cirrhosis and portal hypertension is an easy diagnosis as there will be multiple signs visible to the eye and touch. Any good gastro or hepatologist can find it on physical exam. The harden, nodular liver. The enlarged spleen.

Blood pressure inside the vein can be measured but more often other signs of portal hypertension will be seen on imaging. Varices, ascites, etc. This only happens in stage 4 cirrhosis.

Lisinopril is an ACE inhibitor and the mechanism of the agent is to dilate vessels to reduce hypertension. Metoprolol is in a group of drugs called beta-blockers. Beta-blockers affect the heart and circulation (blood flow through arteries and veins). Metoprolol is used to treat angina and hypertension for high blood pressure. It is also used to treat or prevent heart attack. My regimen is Lisinopril and coreg (beta blocker).

"....my dr wrote in my file "fatty liver infiltration with biliary venous portal hypertension and splenomegaly" what does this mean??" Fatty liver infiltration is just what it says. You have a fatty liver which is probably the most common liver disease. In its mild form it isn't a cause for alarm but it can become more advanced and can lead to fibrosis and even cirrhosis - scaring of the liver. That does pose a serious health risk.

i d check fibroscan to know for sure how liver is, i am not very expert on advanced decompensated cirrhosis but portal hypertension happens when we have problems with blood flow in the liver and i guess we need damage for this to happen raw organic cocoa beans, berries over 160g per day and organic black rise do help.

If you had a liver transplant, you would no longer have portal hypertension. And as long as the portal hypertension is the only cause for the pulmonary hypertension, then you would theoretically be cured.

Scar tissue in the liver (cirrhosis) can interfere with that blood flow, causing pressure to build up in the portal vein (portal hypertension), and the spleen to enlarge (splenomegaly). As the spleen enlarges, it traps more and more platelets. (The amount of platelets in the bloodstream is reduced because the spleen is busy trapping them).

Whether celiac disease can cause portal hypertention in some way I do not know. But I can explain cirrhosis and portal hypertension and their relationship in typical liver disease caused by most causes of liver disease such as alcoholic liver disease, hepatitis B and C infection, fatty liver disease etc. Typically cirrhosis of the liver is easy to diagnose. With a one minute physical exam a doctor should be able to detect if someone has cirrhosis.

Once your liver has become fibrotic enough to cause portal hypertension, then your collateral vessels will be affected (if linked to the portal venous system). But these are mostly internal as in: gastric varices, esophageal varices or other upper and lower GI collaterals. Your outer surface stomach region may show some strange vein issues due to the recanalisation of the paraumbilical vein, but these are quite pronounced (scary looking too, called "caput medusae").

The preferred, albeit indirect, method for assessing portal pressure is the wedged hepatic venous pressure (WHVP) measurement, which is obtained by placing a catheter in the hepatic vein and wedging it into a small branch or, better still, by inﬂating a balloon and occluding a larger branch of the hepatic vein. This is rarely done as the exact pressure is not needed and what is important is to stop the resulting complications such as life-threatening variceal bleeds. Also .

2) there is fluid back up from the liver or large blood vessels into the peritoneal cavity -- known as portal hypertension; 3) low protein state in the body; and 4) miscellaneous.

Portal hypertension is not a death sentence. It's a diagnosis - and you don't really have even that yet. You said 'think he said portal hypertension', so you don't really have a true idea of what's going on. In most cases the effects of portal hypertension can be managed through diet, lifestyle changes, medications, endoscopic therapy, surgery, or radiology.

All cirrhotics will develop portal hypertension. That means increased pressure in the portal venous system. The severity varies widely. The main reason is narrowing of the portal vein branches by fibroblasts ( scar tissue). After SVR, the scar tissue is resorbed, the portal vein branches can dilate and the pressure decreases. This is why cirrhotics won't develop new varices after SVR, and existing varices may shrink.

Has your husband had sxs. from portal hypertension? Is it something you can feel , like a sense of vague aching in the area of the liver? I'm told the liver has no nerve endings? But I know I'm not imagining this discomfort.

First observation I know is correct, Coreg and Carvedilol are the exact same drug, except Carvedilol is the generic form of Coreg. Increasing the combination would mean over 120mg, an unheard of dosage. You are already taking a gorilla dose and that can cause a drop of EF in my opinion. EF ratings fluctuate. I'd ask for a BNP test that is used to determine the level of CHF one has. Usually less than 100 indicates no CHF.

Carvedilol in portal hypertension

Common Questions and Answers about Carvedilol in portal hypertension

coreg