Hi Idyllic, Thanks for a great answer. My source is the medication guide that came with the Victrellis. At the bottom of the page it states: Your healthcare provider may need to monitor your therapy more closely if you take Victrellis with the following medications: alprazolam, amiodarone, atorvastatin, bepridil, bosentan, budesonide, buprenorphine, cyclosporine, desipramine, digoxin.
It doesn't mention methadone. Makes me wonder if treatment is harder with buprenorphine.