If a grand mal seizure lasts for a long time in a person with seizure it can lead to brain
damage. Seizures are caused by brain
scarring, infections such as meningitis, tumors, surgery, stroke, and Alzheimer’s and related diseases. They can be triggered by stress, lack of sleep, infection, alcohol, and certain medications and, in children, fevers. Similarly brain damage from traumatic injury, brain tumor, a lack of oxygen to the brain all can lead to scar tissue to form.