"Efficacy of an experimental azithromycin
cream for prophylaxis of tick-transmitted lyme disease
spirochete infection in a murine model."
" a single application of 4% azithromycin
cream was 100% protective when applied directly to the tick bite site at the time of tick removal. "
cream formulations appear to hold promise for lyme disease
The word is 'prophylaxis' not 'treatment'.