So recurrent urethritis is nearly never due to
gonorrhea or chlamydia
, unless the patient was reinfected.
Mycoplasma are harder to
eradicate for a few reasons. Many strains are resistant to antibiotics, especially tetracycline resistance. This means doxycycline, a commonly prescribed drug, will often fail in treatment. Resistance rates of 50% have been reported for ureaplasma and doxycycline. M hominis is resistant to erythromycin, azithromycin, and clarithromycin.