Atorvastatin hepatotoxicity

Common Questions and Answers about Atorvastatin hepatotoxicity

lipitor

Is atorvastatin or pravastatin better at monitoring cholestoral? My doctor prescribed the generic pravastatin as a more afordable alternative to atorvastatin but also doubled the amount I take (from 20 mg of atorvastatin to 40 mg of pravastatin). Should I be concerned about the effectiveness of pravastatin?

It is easy to find information regarding drug-drug interactions for omeprazole (Prilosec) and atorvastatin (Lipitor). The omeprazole appears to increase the bioavailability of the statin, increasing the risk of side effects. Does this mean that the interaction is like taking a higher dose of the statin, which would provide benefit for someone like me who only takes a low dose (10mg atorvastatin daily) and has no statin tolerance issues?

I have used 10mg Atorvastatin for years with no side effects. The doctor is switching me to simvastatin which reacted badly with my liver in the past. Aim is to save money. Is it safe to buy Atorvastatin online ?

What is the statistic probability that Atorvastatin Ca will convert itself into his enantiomer? We believe that this conversion is improbable for 2 reasons First it requires breaking bonds in two different chiral sites in the molecule which will require substantial energy and will not happen spontaneously Second the statistical probability that the reforming of the bond in the enantiomer in this very specific way is close to zero. We would be appreciative to hear your opinion.

She is not alcoholically person and never drink in her live. She has heart disease and take atorvastatin for 10 years and also donepezil and ladiomil for 4 years. Since her doctor discover problem with GOT and GPT she stopped taking atorvastatin (3mounts before) because they were suspicious that atorvastatin was reason for this problem but again GOP and GPT increase. Next step was cancer marker (CA19-9 = 34.4, AST = 5.47, CEA=3.22) and virus markers (HBsAg Es = 0.13 negative, Anti-HCV = 0.

If the atorvastatin is keeping your triglycerides down, you will need to continue taking this medication for life, UNLESS, you can get the trigs down thru diet. I assume you tried this before being prescribed the medication. Your trigs are currently 1.48mmol/L which is below the limit required for safety (1.7). You are only taking a very small dosage of Atorvastatin, most people are on 40mg daily.

Tuberculosis was more common in alcoholic and Child class C cirrhosis (Table 1). Antituberculosis therapy (ATT) is associated with hepatotoxicity in 10%. Hepatotoxicity requires withdrawal, modification, and sequential reintroduction to achieve cure of tuberculosis. Using such hepatotoxic drugs in presence of cirrhosis or advanced liver disease is a challenge.

Although clinically significant liver injury is extremely rare from statins, mild increases in liver enzymes can occur in 1%–3% of patients. Because of the concern of possible hepatotoxicity, statins are labeled as contraindicated in patients with liver disease. Given the prevalence of liver diseases in the population, such as nonalcoholic fatty liver disease (NAFLD), hepatitis C (HCV), and others, many patients have not benefitted from the cardiovascular protective effects of statins.

My endocrinologist prescribed me Atorvastatin 40mg in place of the simvastatin but it has since given my major chest pain and muscle weakness in my fingers and legs; so I was advised by the pharmacist to stop that and I have only taken the new statin twice and tonight was the second time taking it. Is simvastatin something that can be eased up to a higher dose to do the exact same thing atorvastatin does for the bad cholesterol?

My mother has been put on Atorvastatin and within one week she has had extreme confusion and forgetfulness. This has been the only medical change. Is this a side effect from it and can they show up this quickly?

He prescribed Atorvastatin in addition to vitamins but I did a small research about Atorvastatin and find out there are some contradictions about usefulness of Atorvastatin. Of course the contradiction relates to use of Atorvastatin in combination of interferons and he prescribed Atorvastatin in combination with vitamins but I have not decided whether I use it or not. 1->http://www.ncbi.nlm.nih.gov/pubmed/18398457 2->http://www.ncbi.nlm.nih.

57 Male never on medication and gym rat. I have been on Atorvastatin 40mg since middle of March. It was prescribed by my cardiologist for slightly high cholesterol level 225. Along with BP Med Losartan 50mg. All of this started when I wasn't feeling very well one day in February and went to outpatient clinic. Since then I've had a heart monitor, CT scan of heart and angiogram. All normal except angiogram showed one 70% blockage.

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