In a drug safety communication, the agency warned that there are important drug
interactions between boceprevir (Victrelis) and anti-HIV protease inhibitors boosted with ritonavir (Norvir).
Boceprevir, approved last year, is a novel direct-acting agent targeting the NS3/4A protease of hepatitis C. It's taken with ribavirin and pegylated interferon-alfa to treat genotype 1 disease.