Arimidex in premenopausal women
Common Questions and Answers about Arimidex in premenopausal women
arimidex
Early results from this study indicate that Zometa in combination with endocrine therapy (goserelin plus tamoxifen or goserelin plus arimidex) lowers the 5-year risk for breast cancer recurrence by 36% compared to those women who were being given endocrine therapy alone. Zometa apparently not only prevented bone metastases, but metastases to other body parts as well. It also decreased recurrence risk in the unaffected breast.
Hi,
I found this information for you.I am also taking Arimidex and of course I am very interested in knowing more about this medication.My breast surgeon told me also that by taking Arimidex reduces the development of new breast cancers by 50 per cent.
-----------------------------------------
Arimidex most effective in breast cancer study.
s cancer is ER/PR positive,the patient will have a better than average prognosis, and their cancer is likely to respond to endocrine therapy (anti-hormone treatments)such as Tamoxifen if premenopausal or Arimidex/Femara if postmenopausal.These drugs shut down the body's ability to make estrogen which is a hormone that fuels many breast cancer tumors.
Please keep in mind though that even something seemingly as harmless as this should be ONLY WITH your Oncologist's approval.
What do the studies show happens to women who are caught early, have breasts removed, no lymph involvement and who do NOT take Arimidex or tamoxifen?
Based on information from a study in patients with early breast cancer, women with a history of blockages in heart arteries (ischemic heart disease) who take ARIMIDEX may have a slight increase in this type of heart disease compared to similar patients who take tamoxifen.
ARIMIDEX can cause bone softening/weakening (osteoporosis) increasing the chance of fractures.
Tamoxifen can be used by both premenopausal and postmenopausal women. In premenopausal women, tamoxifen will not make the patient menopausal. The ovaries will still continue to produce estrogen. This is where the role ovarian ablation plays. Ovarian ablation can be accomplished by ovarian irradiation, surgery, or use of gonadotropin hormone-releasing hormone (GnRH) and leutenizing hormone-releasing hormone (LHRH) agonists.
Hello, I am a 42 year old woman. I not had a period in two months and am having menopausal symptoms, i.e. hot flashes, headaches, weight gain, irritability, etc.
I had my annual check-up with my OB/Gyn and he ran some blood work. The nurse called me with the results and said everything was normal except my Vitamin D levels, and for that I have started taking supplements. She could give me no reason for why I have stopped having a period beyond her explanation of stress.
A cancerous lump was found in my right breast in 2004 and I had lumpechtomy performed whereby it was removed. Shortly thereafter, I had 35 sessions of radiation. The cancer has not returned (I take Arimidex). However, I my ribs underneath my breast are very painful - they can hardly tolerate any touch or pressure. My Oncologist has told me that every women she has treated for the same also complain about bone pain on the site where the radiation took place. What is the reason for this?
Hi Kelsey:
Thank you for your response, it is much appreciated. I will see my family doctor on Tuesday to get my dexa score. But for now I'm concerned with my reaction to the Arimidex. I took my first dose last Tuesday morning at 9:30am, at 12:30p I went to bed for a few hours. Long story, short....I've been feeling horrible since last Tuesday. No energy, very tired and shaky, MENTAL FOG, very emotional, I've cried at least one time everyday since.
I am a stage IV survivor. I was diagnosed with cancer for the second time in my breast in 2006. This time it mastisized to my right femur which was treated with 10 treatments of radiation. The breast was removed. I have been on Arimidex 6 years now. I have gradually gained 40 pounds, continually have hot flashes and night sweats, have joint pain and now starting to retain water/have diarreah.
Can anyone tell me anything about half dose of arimidex. I recently started with the 1mg dose of arimidex (standard) and feel horrible. Tired, shaky, mental fog, very emotional. I weigh only 124lb and recently had my ovaries removed, so my question is: why do I have to take the full 1mg of Armidex when women who are heavier than me and still have their ovaries take the same dosage. Will a half dose or every other day dose be just as effective for me?
We hypothesized that a transvaginal endometrial stripe of less than 5 mm in premenopausal women would exclude endometrial polyps and intracavitary leiomyomata, thereby eliminating the need for sonohysterography.
ref: http://www.greenjournal.org/cgi/content/full/104/1/120
So this study suggests that there could be uterine pathology-tumor/mass could be present but further investigations are required along with your clinical history before any conclusion can be made.
we all have our own values and beliefs. Arimidex is often given after Tamoxifen to post-menopausal women ... I would like to add though that you cannot go by what someone else has experienced. Each and every person as well as their medical case is vastly different ... one person's reaction has nothing to do with another's. Do whatever gives you peace of mind and remember that you are the one who will experience the results of your decision ... Regards ....
Recommended
