Arimidex hormone therapy
Common Questions and Answers about Arimidex hormone therapy
arimidex
Lymph nodes clear. After surgery had mammosite. Should I do hormone therapy? I also had ovarian cancer 2 yrs. ago. Stage 1A also. Doing well here.
Took chemo for OV. and left me with aching legs and joints. The hormone therapy has so many side affects. The drugs suggested for me are Arimidex or Raloxifene. Is there anyone that does not take hormone therapy and is still doing well with no recurrance?
I have been told from the start that with a lumpectomy I would need radiation. I found out later about the hormone therapy. I want to know if this is standard of care for my situation. I had a 1cm lump including DCIS and ILC. My margins were 6mm, 1cm, 5cm, 6cm. The ILC was in a linear pattern and low nuclear grade. 4 of 4 nodes were negative for cancer. I am ER+ 100% and PR+ 90%. I am HER2 negative. I was told my cancer was caught very early and I should be OK.
A recent study confirmed the long-term superior efficacy and safety of anastrozole (Arimidex) over tamoxifen as initial adjuvant therapy for postmenopausal women with hormone-sensitive early breast cancer.
It is apparently considered likely that this would hold true for the other AIs, such as Aromasin, but if you wish, you could ask your doctor about the possibility of trying Arimidex in place of Aromasin.
Best wishes...
It is the hormone that is recommended for women with ER/PR positive breast cancer who are premenopausal or postmenopausal. Arimidex (or other aromatase inhibitors) is another class of hormone therapy that also blocks estrogen to breast tissue but these drugs are only offered to women who are postmenopausal. Both tamoxifen and armidex only address the ER/PR status and do not have any impact on CerbB2.
ve completed 4 cycles of Taxotere and Cytoxan. I have been on Arimidex for 4 months. What might be my chances of a distant metastasis? I have pre-osteopenia per a bone density. My oncologist said I might consider Zometa infusions which would be given every 6 months. Does it only help prevent bone metastasis or other mets as well? I know the research is still out on this but an early study indicated a greater than 30% reduction in risk of bone mets. That seems substantial.
Even though her pathology showed a negative hormone receptor her oncologist is saying that they are now finding arimidex to slow the growth of tumors in some patients that had a long time from initial breast cancer treatment to a recurrence. Has anyone else heard of this? I'm wondering if the HMO is trying to lower their cost of her care using this instead of the Chemotherapy Adriamyacin. It would, however, be a great thing if it actually works.
Thanks for any advice!
That could very likely be the reason ... if I were you I would certainly bring it up when you go for your ck. up. If that was his recommendation and you were OK with it initially I can't see any reason to have ask before. Personally I would like to know the reasoning though .... as no doubt you would too, so ask away. Best Wishes for your ck. up.
Last week the doctor had me switch to Arimidex as I had not had a period for one year. After taking it for a couple of days I was not feeling very well. I was having stomach discomfort, irratibility and swelling in my hands. I received a call from the doctor's office telling me not to take the Arimidex and return to Tamoxifen as my hormone levels suggested that I wasn't in menopause quite yet.
How do these two drugs work differently?
Bioidentical or synthetic, it is still hormone therapy. In fact, the purpose of arimidex is to remove any estrogen that may be produced outside the ovaries. Research has shown that this significantly reduces the risk of recurrence. There are additional methods that could be tried to reduce hot flushes and you may want to seek out a specialist/oncologist who is familiar with working with women like yourself.
NEW YORK (Reuters Health) - After approximately 8 years, postmenopausal women with hormone-sensitive breast cancer who received (Arimidex), generically known as anastrazole, had a lower risk of recurrence than women taking tamoxifen, investigators reported at the annual meeting of the San Antonio Breast Cancer Symposium.
After an average of 68 months, women on Arimidex had a 15-percent greater disease-free survival and a 25-percent longer time to disease recurrence than women on tamoxifen.
Hi,
I had the same type of breast cancer you had.Stage 1,clean margins as well as clean Sentinel lymph nodes. My tumor was 9mm.My treatment was 20 radiation sessions and since I am post menopausal I am taking and will continue to take Arimidex for as long as my Surgeon will advise me to do so.If your surgeon thinks that all you need is radiation and hormone therapy..then this is maybe all you really need.
Dear madwilson, Hairloss is not a usual side effect associated with Arimidex. Arimidex is an aromatase inhibitor. This means it blocks the enzyme aromatase (found in the body's muscle, skin, breast and fat), which is used to convert androgens (hormones produced by the adrenal glands) into estrogen. In the absence of estrogen, tumors dependent on this hormone for growth will shrink. For more information regarding this drug and side effects you can check out the website chemocare.com.
I don't recall anyone posting regarding similar issues but I would advise you to NOT consider any treatments until you have seen the Endocrinoligist next month. It certainly seems to be hormone related and it could also indicate early menopause. Any type of hormone replacement therapy doesn't seem wise at this point .... My best advise would be to hang in there until the Endocrinology consult. Regards ....
s cancer is ER/PR positive,the patient will have a better than average prognosis, and their cancer is likely to respond to endocrine therapy (anti-hormone treatments)such as Tamoxifen if premenopausal or Arimidex/Femara if postmenopausal.These drugs shut down the body's ability to make estrogen which is a hormone that fuels many breast cancer tumors.
Does Arimidex have to actually kill you vs. maiming you for life, in order to be pulled off the market? At 58, I may need a hip replacement because I took Arimidex for two years! DeeDee
This discussion is related to <a href='http://www.medhelp.org/posts/show/260593'>Arimidex Long Term Side Effects</a>.
If her cancer is estrogen receptor positive as well as being slow growing, then the hormone therapies like Femara, Aromasin, Arimidex, etc. seem to be the best choice at the moment. Those are drugs that were primarily given to post chemo breast cancer patients since breast cancer is usually estrogen related.
I was diagnosed at age 49 in May, 2007 with Stage II, 3 nodes positive. I had 4 rounds of A/C and 4 rounds of Taxol followed by 33 rounds of radiation. My doctor now wants to put me on hormone therapy. I am premenopausal but haven't gotten my period since July due to chemo. She won't put me on Tamoxifin because of a past history of TIA several years ago. She said I would be at too high a risk for stroke on it.
Recommended
