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Introduction
Background
Sertoli-cell-only (SCO) syndrome, also called germ cell aplasia, describes a condition of the testes in which only Sertoli cells line the seminiferous tubules. Typically, these
men present between age 20-40 years
for evaluation of
infertility and are found to be azoospermic, a term describing the absence of sperm in the ejaculate. Physical examination is often unremarkable, and the diagnosis is made based on testicular biopsy findings.