Hi, Loratadine is a second generation antihistamine
and considered relatively unsafe in preganancy. First-generation antihistamine
s are considered safe to use during pregnancy. Examples of first-generation antihistamine
s are brompheniramine, chlorpheniramine, dimenhydrinate, diphenhydramine, doxylamine, hydroxyzine, and pheniramine. None of the medications in this class of drugs has been reported to increase fetal risk when used at any time during pregnancy.