I contacted the company and asked them if their Clear Eyes Pure Relief Multi Symptom Preservative Free eye drops had antihistamine (which I cannot take). There answer was "4/4/2017 "We like to advise you that the product contains the following ingredients phenylephrine hydrochloride, glycerin, hypromellose, citric acid, purified water, sodium chloride, and sodium citrate. We have no indication of whether or not the product contains antihistamine.