I have suffered depression all of my life, feeling sad as far back into childhood as I can remember. I spent many, many years self-medicating (alcohol+
drugs). I know for me, I have tried 16 different anti-depressants and other than the ones that gave me severe nausea and the ones that made me feel like a walking Zombie (Effexor, Seroquel and Olanzapine), the others did nothing.