Lately, the role of vitamin D has been revised regarding its potential advantage on delaying the process of
aging. The aim of this study was to assess the contribution of VDR
gene polymorphisms in healthy aging and longevity.
We evaluated the frequency of four polymorphisms of the VDR gene (FokI, BsmI, ApaI, and TaqI) in centenarians (102 subjects, mean age: 102.3 ± 0.3 years), compared to septuagenarians (163 subjects, mean age: 73.0 ± 0.